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A finer print than TADs: PRC1-mediated domains

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Item Type:Editorial
Title:A finer print than TADs: PRC1-mediated domains
Creators Name:Torlai Triglia, E. and Rito, Tiago and Pombo, A.
Abstract:Polycomb proteins are well-known epigenetic repressors with unexplained roles in chromatin folding. In this issue of Molecular Cell, Kundu et al. (2017) investigate the structures of PRC1-mediated domains in stem cells and probe their changes upon differentiation and in PRC knockouts.
Keywords:Cell Differentiation, Chromatin, Embryonic Stem Cells, Genetic Epigenesis, Polycomb Repressive Complex 1, Protein Domains, Animals
Source:Molecular Cell
ISSN:1097-2765
Publisher:Cell Press
Volume:65
Number:3
Page Range:373-375
Date:2 February 2017
Official Publication:https://doi.org/10.1016/j.molcel.2017.01.028
PubMed:View item in PubMed

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