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Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles

Item Type:Article
Title:Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles
Creators Name:Bel Abed, H., Schoene, J., Christmann, M. and Nazare, M.
Abstract:A convenient and efficient strategy has been devised to access 3-amino-2H-indazole derivatives in two steps from readily available starting materials. The conversion of 2-nitrobenzonitriles to substituted benzamidines followed by an organophosphorus-mediated reductive cyclization and a subsequent N-N bond formation afforded 3-amino-2H-indazoles in good to excellent yields.
Source:Organic & Biomolecular Chemistry
ISSN:1477-0520
Publisher:Royal Society of Chemistry
Volume:14
Number:36
Page Range:8520-8528
Date:28 September 2016
Official Publication:https://doi.org/10.1039/c6ob01544a
PubMed:View item in PubMed

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