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| Item Type: | Editorial |
|---|---|
| Title: | Orchestrating Wnt signalling for metabolic liver zonation |
| Creators: |
Birchmeier, W.  ORCID: https://orcid.org/0000-0003-1173-0829
|
| Abstract: | Wnt/{beta}-catenin signalling is an important regulator of liver development, zonation and regeneration. The cell surface complex RSPO-LGR4/5-ZNF3/RNF43 is now shown to direct Wnt/{beta}-catenin signalling in orchestrating the division of the liver into functionally distinct metabolic zones, providing insights into the mechanisms that influence organ development and regeneration. |
| Keywords: | Liver, Signal Transduction, Wnt Proteins, Beta Catenin |
| Source: | Nature Cell Biology |
| ISSN: | 1465-7392 |
| Publisher: | Nature Publishing Group |
| Volume: | 18 |
| Number: | 5 |
| Page Range: | 463-465 |
| Date: | May 2016 |
| Official Publication: | https://doi.org/10.1038/ncb3349 |
| PubMed: | View item in PubMed |
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