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SL2: an interactive webtool for modeling of missing segments in proteins

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Item Type:Article
Title:SL2: an interactive webtool for modeling of missing segments in proteins
Creators Name:Ismer, J. and Rose, A.S. and Tiemann, J.K.S. and Goede, A. and Preissner, R. and Hildebrand, P.W.
Abstract:SuperLooper2 (SL2) (http://proteinformatics.charite.de/sl2) is the updated version of our previous web-server SuperLooper, a fragment based tool for the prediction and interactive placement of loop structures into globular and helical membrane proteins. In comparison to our previous version, SL2 benefits from both a considerably enlarged database of fragments derived from high-resolution 3D protein structures of globular and helical membrane proteins, and the integration of a new protein viewer. The database, now with double the content, significantly improved the coverage of fragment conformations and prediction quality. The employment of the NGL viewer for visualization of the protein under investigation and interactive selection of appropriate loops makes SL2 independent of third-party plug-ins and additional installations.
Keywords:Protein Databases, Internet, Molecular Models, Peptide Fragments, Protein Conformation, Proteins, Software, User-Computer Interface
Source:Nucleic Acids Research
ISSN:0305-1048
Publisher:Oxford University Press
Volume:44
Number:W1
Page Range:W390-W394
Date:8 July 2016
Official Publication:https://doi.org/10.1093/nar/gkw297
PubMed:View item in PubMed

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