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Increased periodontal attachment loss in patients with systemic sclerosis

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Item Type:Article
Title:Increased periodontal attachment loss in patients with systemic sclerosis
Creators Name:Pischon, N. and Hoedke, D. and Kurth, S. and Lee, P. and Dommisch, H. and Steinbrecher, A. and Pischon, T. and Burmester, G.R. and Buttgereit, F. and Detert, J. and Riemekasten, G.
Abstract:Background: Patients with inflammatory rheumatic diseases and periodontitis share common pathogenetic characteristics, such as pro-inflammatory traits causative for tissue degradation and loss of function. Aim of the present case control study was to investigate the association between systemic sclerosis (SSc) and periodontitis. Methods: The association between SSc and periodontitis was examined in 58 SSc patients and 52 control patients, matched for age and gender. Periodontal examination included periodontal attachment loss, probing pocket depth, bleeding on probing, plaque index and gingival index. Potential risk factors of periodontitis were assessed through patients' questionnaires. Results: In unadjusted analyses, patients with SSc had a significant 0.61 mm higher periodontal attachment loss (95 % confidence interval (CI), 0.24 - 0.97; p = 0.002) when compared to controls. In a stepwise logistic regression, including SSc status, age, gender, education, smoking, alcohol consumption and BMI, only SSc status, age, and gender remained significantly associated with periodontitis. Adjusted for age and gender, patients with SSc had 0.52 mm higher periodontal attachment loss compared to controls (95 % CI, 0.16 - 0.88; p = 0.005). The strength of the association of SSc with periodontal attachment loss remained statistically significant after further adjustment for plaque index (0.44 mm; 95 % CI 0.02 - 0.86; p = 0.038) or gingival index (0.61 mm; 95 % CI, 0.24 - 0.97 p = 0.001). Conclusions: The study demonstrates higher periodontal clinical attachment loss in SSc patients, which remained significant following adjustment. The study indicates a possible relationship between SSc and periodontitis.
Keywords:Systemic Sclerosis (SSc), Periodontitis, Risk Factors, Inflammation, Infection
Source:Journal of Periodontology
Publisher:American Academy of Periodontology
Page Range:763-771
Date:July 2016
Official Publication:https://doi.org/10.1902/jop.2016.150475
PubMed:View item in PubMed

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