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Immunological memory: lessons from the past and a look to the future

Official URL:https://doi.org/10.1038/nri.2016.13
PubMed:View item in PubMed
Creators Name:Farber, D.L. and Netea, M.G. and Radbruch, A. and Rajewsky, K. and Zinkernagel, R.M.
Journal Title:Nature Reviews Immunology
Journal Abbreviation:Nat Rev Immunol
Volume:16
Number:2
Page Range:124-128
Date:February 2016
Keywords:20th Century History, 21st CenturyHistory, Allergy and Immunology, Immunologic Memory, Innate Immunity, T-Lymphocyte Subsets, T-Lymphocytes
Abstract:Immunological memory is considered to be one of the cardinal features of the adaptive immune system. Despite being a recognized phenomenon since the time of the ancient Greeks, immunologists are yet to fully appreciate the mechanisms that control memory responses in the immune system. Furthermore, our definition of immunological memory itself continues to evolve, with recent suggestions that innate immune cells also show memory-like behaviour. In this Viewpoint article, Nature Reviews Immunology invites five leading immunologists to share their thoughts on our current understanding of the nature of immunological memory. Our experts highlight some of the seminal studies that have shaped the immune memory field and offer contrasting views on the key questions that remain to be addressed.
ISSN:1474-1733
Publisher:Nature Publishing Group (U.K.)
Item Type:Article

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