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Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management

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Item Type:Review
Title:Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
Creators Name:Sinnecker, T. and Kuchling, J. and Dusek, P. and Dörr, J. and Niendorf, T. and Paul, F. and Wuerfel, J.
Abstract:Conventional magnetic resonance imaging (MRI) at 1.5 Tesla (T) is limited by modest spatial resolution and signal-to-noise ratio (SNR), impeding the identification and classification of inflammatory central nervous system changes in current clinical practice. Gaining from enhanced susceptibility effects and improved SNR, ultrahigh field MRI at 7 T depicts inflammatory brain lesions in great detail. This review summarises recent reports on 7 T MRI in neuroinflammatory diseases and addresses the question as to whether ultrahigh field MRI may eventually improve clinical decision-making and personalised disease management.
Keywords:7 Tesla, Ultrahigh field MRI, Multiple sclerosis, Neuromyelitis optica, Susac syndrome, Neuroimmunology, Central vein sign, Cortical lesions, Predictive, Preventive and Personalised Medicine
Source:EPMA Journal
ISSN:1878-5077
Publisher:BioMed Central (U.K.)
Volume:6
Number:1
Page Range:16
Date:27 August 2015
Official Publication:https://doi.org/10.1186/s13167-015-0038-y
PubMed:View item in PubMed

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