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Crosstalk between two bZIP signaling pathways orchestrates salt-induced metabolic reprogramming in arabidopsis roots

Item Type:Article
Title:Crosstalk between two bZIP signaling pathways orchestrates salt-induced metabolic reprogramming in arabidopsis roots
Creators Name:Hartmann, L. and Pedrotti, L. and Weiste, C. and Fekete, A. and Schierstaedt, J. and Göttler, J. and Kempa, S. and Krischke, M. and Dietrich, K. and Mueller, M.J. and Vicente-Carbajosa, J. and Hanson, J. and Dröge-Laser, W.
Abstract:Soil salinity increasingly causes crop losses worldwide. Although roots are the primary targets of salt stress, the signaling networks that facilitate metabolic reprogramming to induce stress tolerance are less understood than those in leaves. Here, a combination of transcriptomic and metabolic approaches was performed in salt-treated Arabidopsis thaliana roots, which revealed that the group S1 basic leucine zipper transcription factors bZIP1 and bZIP53 reprogram primary C- and N-metabolism. In particular, gluconeogenesis and amino acid catabolism are affected by these transcription factors. Importantly, bZIP1 expression reflects cellular stress and energy status in roots. In addition to the well-described abiotic stress response pathway initiated by the hormone abscisic acid (ABA) and executed by SnRK2 (Snf1-RELATED-PROTEIN-KINASE2) and AREB-like bZIP factors, we identify a structurally related ABA-independent signaling module consisting of SnRK1s and S1 bZIPs. Crosstalk between these signaling pathways recruits particular bZIP factor combinations to establish at least four distinct gene expression patterns. Understanding this signaling network provides a framework for securing future crop productivity.
Keywords:Abscisic Acid, Amino Acids, Arabidopsis, Arabidopsis Proteins, Basic-Leucine Zipper Transcription Factors, Calcium, Carbohydrate Metabolism, Genetic Promoter Regions, Gluconeogenesis, Immunoblotting, Mutation, Plant Gene Expression Regulation, Plant Growth Regulators, Plant Roots, Protein Binding, Protein-Serine-Threonine Kinases, Reverse Transcriptase Polymerase Chain Reaction, Salt-Tolerant Plants, Signal Transduction, Sodium Chloride, Transcriptome
Source:Plant Cell
Publisher:American Society of Plant Biologists
Page Range:2244-2260
Date:August 2015
Official Publication:https://doi.org/10.1105/tpc.15.00163
PubMed:View item in PubMed

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