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Resistente Hypertonie : Was ist das? [Resistant hypertension : What is it?]

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Item Type:Article
Title:Resistente Hypertonie : Was ist das? [Resistant hypertension : What is it?]
Creators Name:Luft, F.C.
Abstract:When blood pressure is poorly controlled despite treatment with a diuretic and two antihypertensive drugs at adequate doses, the hypertension is termed resistant. The prevalence of resistant hypertension is increasing. Once pseudo-resistance due to poor compliance, secondary forms of hypertension, and massive salt consumption have been excluded, some authorities maintain that blood pressure can be invariably lowered using minoxidil or mineralocorticoid receptor blockade. I also adhered to this belief until we encountered a patient who despite treatment with seven antihypertensive agents, electrical carotid sinus stimulation, and catheter-based renal denervation continued to exhibit extraordinarily high blood pressure values. I am now convinced that resistant hypertension does indeed exist. The prevalence of such patients can be substantially reduced by means of a thorough history and physical examination, determining drug serum concentrations, and excluding secondary causes.
Keywords:Medication Adherence, Hypertension, Secondary, White Coat Hypertension, Life Style, Minoxidil
Publisher:Springer (Germany)
Page Range:224-229
Date:March 2015
Official Publication:https://doi.org/10.1007/s00108-014-3568-9
PubMed:View item in PubMed

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