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Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation

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Item Type:Article
Title:Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation
Creators Name:Oberender, C. and Kleeberg, L. and Nienhues, N. and Gresse, M. and Doerken, B. and Riess, H. and le Coutre, P.
Abstract:Chronic myeloid leukemia developing after transplantation of solid organs and concomitant immunosuppression is a rare but still significant clinical phenomenon. We here describe an additional case of a 62-year-old male patient developing CML after orthotopic heart transplantation and medication with cyclosporine A, mofetil-mycophenolate, and steroids. Initial antileukemic therapy was imatinib at a standard dose and within 15 months of therapy a complete cytogenetic response was noted. In this report we discuss the clinical implications of these rare but biologically important cases.
Source:Case Reports in Hematology
ISSN:2090-6579
Publisher:Hindawi Publishing (Egypt)
Volume:2014
Page Range:890438
Date:16 November 2014
Official Publication:https://doi.org/10.1155/2014/890438
PubMed:View item in PubMed

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