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Lymphotoxin-{alpha} keeps the gate open for T-cell infiltration in cHL

Item Type:Editorial
Title:Lymphotoxin-{alpha} keeps the gate open for T-cell infiltration in cHL
Creators Name:Hoepken, U.E.
Abstract:In this issue of Blood, Fhu et al report that Reed-Sternberg cell-derived lymphotoxin-{alpha} activates endothelial cells to enhance T-cell recruitment in classical Hodgkin lymphoma (cHL), a process that is regulated by cyclooxygenase/nuclear factor-{kappa}B/activator protein 1 signaling pathways.
Keywords:CD4-Positive T-Lymphocytes, Cell Communication, Endothelial Cells, Hodgkin Disease, Lymphotoxin-alpha, Reed-Sternberg Cells
Source:Blood
ISSN:0006-4971
Publisher:American Society of Hematology (U.S.A.)
Volume:124
Number:19
Page Range:2897-2898
Date:6 November 2014
Official Publication:https://doi.org/10.1182/blood-2014-09-597682
PubMed:View item in PubMed

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