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Vessel labeling in combined confocal scanning laser ophthalmoscopy and optical coherence tomography Images : criteria for blood vessel discrimination

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Item Type:Article
Title:Vessel labeling in combined confocal scanning laser ophthalmoscopy and optical coherence tomography Images : criteria for blood vessel discrimination
Creators Name:Motte, J. and Alten, F. and Ewering, C. and Osada, N. and Kadas, E.M. and Brandt, A.U. and Oberwahrenbrock, T. and Clemens, C.R. and Eter, N. and Paul, F. and Marziniak, M.
Abstract:INTRODUCTION: The diagnostic potential of optical coherence tomography (OCT) in neurological diseases is intensively discussed. Besides the sectional view of the retina, modern OCT scanners produce a simultaneous top-view confocal scanning laser ophthalmoscopy (cSLO) image including the option to evaluate retinal vessels. A correct discrimination between arteries and veins (labeling) is vital for detecting vascular differences between healthy subjects and patients. Up to now, criteria for labeling (cSLO) images generated by OCT scanners do not exist. OBJECTIVE: This study reviewed labeling criteria originally developed for color fundus photography (CFP) images. METHODS: The criteria were modified to reflect the cSLO technique, followed by development of a protocol for labeling blood vessels. These criteria were based on main aspects such as central light reflex, brightness, and vessel thickness, as well as on some additional criteria such as vascular crossing patterns and the context of the vessel tree. RESULTS AND CONCLUSION: They demonstrated excellent inter-rater agreement and validity, which seems to indicate that labeling of images might no longer require more than one rater. This algorithm extends the diagnostic possibilities offered by OCT investigations.
Keywords:Arteries, Computer-Assisted Image Interpretation, Confocal Microscopy, Infrared Rays, Observer Variation, Ophthalmoscopy, Optical Coherence Tomography, Reproducibility of Results, Retina, Staining and Labeling, Veins
Source:PLoS ONE
ISSN:1932-6203
Publisher:Public Library of Science (U.S.A.)
Volume:9
Number:9
Page Range:e102034
Date:9 September 2014
Official Publication:https://doi.org/10.1371/journal.pone.0102034
PubMed:View item in PubMed

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