Mouse models of human cancer

Item Type:	Editorial
Title:	Mouse models of human cancer
Creators Name:	Böck, B.C. and Stein, U. and Schmitt, C.A. and Augustin, H.G.
Abstract:	The Helmholtz Alliance Preclinical Comprehensive Cancer Center (PCCC; www.helmholtz-pccc.de) hosted the "1st International Kloster Seeon Meeting on Mouse Models of Human Cancer" in the Seeon monastery (Germany) from March 8 to 11, 2014. The meeting focused on the development and application of novel mouse models in tumor research and high-throughput technologies to overcome one of the most critical bottlenecks in translational bench-to-bedside tumor biology research. Moreover, the participants discussed basic molecular mechanisms underlying tumor initiation, progression, metastasis, and therapy resistance, which are the prerequisite for the development of novel treatment strategies and clinical applications in cancer therapy.
Keywords:	Animal Disease Models, Biomedical Research, Carcinogenesis, Disease Progression, Germany, Neoplasms, Neoplasm Drug Resistance, Neoplasm Metastasis, Neoplastic Cell Transformation, Animals, Mice
Source:	Cancer Research
ISSN:	0008-5472
Publisher:	American Association for Cancer Research
Volume:	74
Number:	17
Page Range:	4671-4675
Date:	1 September 2014
Official Publication:	https://doi.org/10.1158/0008-5472.CAN-14-1424
PubMed:	View item in PubMed

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