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| Item Type: | Review |
|---|---|
| Title: | Advances in gene targeting methods |
| Creators Name: | Kühn, R. and Schwenk, F. |
| Abstract: | Gene targeting in embryonic stem cells is commonly used for gene inactivation and the generation of mouse mutants. The combined use of methods for site-specific and homologous DNA recombination expands the potential of gene targeting in embryonic stem cells considerably and offers the opportunity of conditional gene targeting in mice. |
| Keywords: | Gene Targeting, Mutant Strains Mice, Animals, Mice |
| Source: | Current Opinion in Immunology |
| ISSN: | 0952-7915 |
| Publisher: | Elsevier |
| Volume: | 9 |
| Number: | 2 |
| Page Range: | 183-188 |
| Date: | April 1997 |
| Official Publication: | https://doi.org/10.1016/S0952-7915(97)80133-1 |
| PubMed: | View item in PubMed |
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