Item Type: | Article |
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Title: | Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants |
Creators Name: | Texidó, G. and Jacobs, H. and Meiering, M. and Kühn, R. and Roes, J. and Müller, W. and Gilfillan, S. and Fujiwara, H. and Kikutani, H. and Yoshida, N. and Amakawa, R. and Benoist, C. and Mathis, D. and Kishimoto, T. and Mak, T.W. and Rajewsky, K. |
Abstract: | We show through sequence analysis of rearranged immunoglobulin variable (Ig-V) region genes from memory B cells of mouse mutants generated by gene targeting that terminal deoxynucleotidyl transferase, CD23, interleukin-4, IgD and CD30 are dispensable for somatic hypermutation. |
Keywords: | Hypermutation, Terminal Deoxynucleotidyl Transferase, CD23, Interleukin-4, IgD, Animals, Mice |
Source: | European Journal of Immunology |
ISSN: | 0014-2980 |
Publisher: | Wiley |
Volume: | 26 |
Number: | 8 |
Page Range: | 1966-1969 |
Date: | August 1996 |
Official Publication: | https://doi.org/10.1002/eji.1830260843 |
PubMed: | View item in PubMed |
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