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A mitochondrial strategy for safeguarding the reprogrammed genome

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Item Type:Comment
Title:A mitochondrial strategy for safeguarding the reprogrammed genome
Creators Name:Prigione, A. and Adjaye, J.
Abstract:Genomic aberrations induced by somatic cell reprogramming are a major drawback for future applications of this technology in regenerative medicine. A new study by Ji et al. published in Stem Cell Reports suggests a counteracting strategy based on balancing the mitochondrial/oxidative stress pathway through antioxidant supplementation.
Keywords:Antioxidants, Mitochondria, Reprogramming, iPSCs, Genomic Aberrations
Source:Cell Regeneration
ISSN:2045-9769
Publisher:BioMed Central (U.K.)
Volume:3
Number:1
Page Range:5
Date:29 March 2014
Official Publication:https://doi.org/10.1186/2045-9769-3-5
PubMed:View item in PubMed

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