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| Item Type: | Comment |
|---|---|
| Title: | A mitochondrial strategy for safeguarding the reprogrammed genome |
| Creators Name: | Prigione, A. and Adjaye, J. |
| Abstract: | Genomic aberrations induced by somatic cell reprogramming are a major drawback for future applications of this technology in regenerative medicine. A new study by Ji et al. published in Stem Cell Reports suggests a counteracting strategy based on balancing the mitochondrial/oxidative stress pathway through antioxidant supplementation. |
| Keywords: | Antioxidants, Mitochondria, Reprogramming, iPSCs, Genomic Aberrations |
| Source: | Cell Regeneration |
| ISSN: | 2045-9769 |
| Publisher: | BioMed Central |
| Volume: | 3 |
| Number: | 1 |
| Page Range: | 5 |
| Date: | 29 March 2014 |
| Official Publication: | https://doi.org/10.1186/2045-9769-3-5 |
| PubMed: | View item in PubMed |
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