Long term recovery in critical illness myopathy is complete, contrary to polyneuropathy

Item Type:	Article
Title:	Long term recovery in critical illness myopathy is complete, contrary to polyneuropathy
Creators Name:	Koch, S. and Wollersheim, T. and Bierbrauer, J. and Haas, K. and Mörgeli, R. and Deja, M. and Spies, C.D. and Spuler, S. and Krebs, M. and Weber-Carstens, S.
Abstract:	Introduction: Muscle weakness in critically ill patients after discharge varies. It is not known whether electrophysiological distinction between critical illness myopathy (CIM) and critical illness polyneuropathy (CIP) during the early part of a patient's stay in the intensive care unit (ICU) predicts long term prognosis. Methods: This was a prospective cohort study of mechanically ventilated ICU patients undergoing conventional nerve conduction studies and direct muscle stimulation in addition to neurological examination during their ICU stay and 1 year following ICU discharge. Results: 26 patients (7 ICU control, 8 CIM patients and 11 CIM/CIP patients) were evaluated 1 year after discharge from the ICU. 88% (n=7) of CIM patients recovered within 1 year, versus 55% (n=6) of CIM/CIP patients. 36% (n=4) of CIM/CIP patients still needed assistance during their daily routine (P=0.005). Discussion: Early electrophysiological testing predicts long term outcome in ICU survivors. CIM has a significant better prognosis than CIM/CIP.
Keywords:	Critical Illness Myopathy, Critical Illness Polyneuropathy, Direct Muscle Stimulation, Intensive Care Unit, Long Term Outcome
Source:	Muscle & Nerve
ISSN:	0148-639X
Publisher:	Wiley-Blackwell
Volume:	50
Number:	3
Page Range:	431-436
Date:	September 2014
Official Publication:	https://doi.org/10.1002/mus.24175
PubMed:	View item in PubMed

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