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Genome function and nuclear architecture: from gene expression to nanoscience

Item Type:Article
Title:Genome function and nuclear architecture: from gene expression to nanoscience
Creators Name:O'Brien, T.P. and Bult, C.J. and Cremer, C. and Grunze, M. and Knowles, B.B. and Langowski, J. and McNally, J. and Pederson, T. and Politz, J.C. and Pombo, A. and Schmahl, G. and Spatz, J.P. and van Driel, R.
Abstract:Biophysical, chemical, and nanoscience approaches to the study of nuclear structure and activity have been developing recently and hold considerable promise. A selection of fundamental problems in genome organization and function are reviewed and discussed in the context of these new perspectives and approaches. Advancing these concepts will require coordinated networks of physicists, chemists, and materials scientists collaborating with cell, developmental, and genome biologists.
Keywords:Cell Nucleus, Computational Biology, Gene Expression Regulation, Genome, Nanotechnology, Animals
Source:Genome Research
Publisher:Cold Spring Harbor Laboratory Press
Page Range:1029-1041
Date:June 2003
Official Publication:https://doi.org/10.1101/gr.946403
PubMed:View item in PubMed

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