Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis

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Item Type:	Review
Title:	Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
Creators Name:	Zinzen, R.P. and Furlong, E.E.
Abstract:	Many essential transcription factors have conserved roles in regulating biological programs, yet their genomic occupancy can diverge significantly. A new study demonstrates that such variations are primarily due to cis-regulatory sequences, rather than differences between the regulators or nuclear environments.
Keywords:	DNA-Directed RNA Polymerases, Gene Regulatory Networks, Genetic Transcription, Molecular Evolution, Species Specificity, Transcription Factors, Animals
Source:	Genome Biology
ISSN:	1465-6906
Publisher:	BioMed Central
Volume:	9
Number:	11
Page Range:	240
Date:	4 November 2008
Official Publication:	https://doi.org/10.1186/gb-2008-9-11-240
PubMed:	View item in PubMed

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