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Mineralocorticoid-receptor signalling in vascular smooth muscle

Item Type:Review
Title:Mineralocorticoid-receptor signalling in vascular smooth muscle
Creators Name:Wu, J. and Luft, F.C.
Abstract:Human data suggest that eplerenone and spironolactone lowers blood pressure by mechanisms independent of the distal tubule. Now, a novel inducible conditional knockout model of the mineralocorticoid receptor (MR) in vascular smooth muscle cells (VSMCs) brings out understanding further.
Keywords:Aldosterone, Cre Recombinase, Hypertension, LoxP, Mineralocorticoid Receptor, Animals
Source:Nephrology Dialysis Transplantation
ISSN:0931-0509
Publisher:Oxford University Press (U.K.)
Volume:28
Number:6
Page Range:1360-1362
Date:June 2013
Official Publication:https://doi.org/10.1093/ndt/gfs562
PubMed:View item in PubMed

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