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Promoter prediction on a genomic scale-the Adh experience

Item Type:Article
Title:Promoter prediction on a genomic scale-the Adh experience
Creators Name:Ohler, U.
Abstract:We describe our statistical system for promoter recognition in genomic DNA with which we took part in the Genome Annotation Assessment Project (GASP1). We applied two versions of the system: the first uses a region-based approach toward transcription start site identification, namely, interpolated Markov chains; the second was a hybrid approach combining regions and signals within a stochastic segment model. We compare the results of both versions with each other and examine how well the application on a genomic scale compares with the results we previously obtained on smaller data sets.
Keywords:Alcohol Dehydrogenase, DNA Sequence Analysis, Factual Databases, Genetic Promoter Regions, Insect Genes, Probability, Software, Animals, Drosophila melanogaster
Source:Genome Research
ISSN:1088-9051
Publisher:Cold Spring Harbor Laboratory Press (U.S.A.)
Volume:10
Number:4
Page Range:539-542
Date:April 2000
Official Publication:https://doi.org/10.1101/gr.10.4.539
PubMed:View item in PubMed

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