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Promoting developmental transcription

Item Type:Review
Title:Promoting developmental transcription
Creators Name:Ohler, U. and Wassarman, D.A.
Abstract:Animal growth and development depend on the precise control of gene expression at the level of transcription. A central role in the regulation of developmental transcription is attributed to transcription factors that bind DNA enhancer elements, which are often located far from gene transcription start sites. Here, we review recent studies that have uncovered significant regulatory functions in developmental transcription for the TFIID basal transcription factors and for the DNA core promoter elements that are located close to transcription start sites.
Keywords:Biological Models, Developmental Gene Expression Regulation, Genetic Promoter Regions, Genetic Transcription, Transcription Factor TFIID, Transcription Initiation Site, Animals
Source:Development
ISSN:0950-1991
Publisher:Company of Biologists (U.K.)
Volume:137
Number:1
Page Range:15-26
Date:January 2010
Official Publication:https://doi.org/10.1242/dev.035493
PubMed:View item in PubMed

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