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Upregulation of myocardial estrogen receptors in human aortic stenosis

Item Type:Article
Title:Upregulation of myocardial estrogen receptors in human aortic stenosis
Creators Name:Nordmeyer, J. and Eder, S. and Mahmoodzadeh, S. and Martus, P. and Fielitz, J. and Bass, J. and Bethke, N. and Zurbruegg, H.R. and Pregla, R. and Hetzer, R. and Regitz-Zagrosek, V.
Abstract:Estrogen receptor (ER)-mediated effects have been associated with the modulation of myocardial hypertrophy in animal models and in humans, but ER expression in the human heart and its relation to hypertrophy-mediated gene expression have not yet been analyzed. We therefore investigated sex- and disease-dependent alterations of myocardial ER expression in human aortic stenosis together with the expression of hypertrophy-related genes.
Keywords:Aortic Valve Stenosis, Estrogen Receptors, Hypertrophy
Source:Circulation
ISSN:0009-7322
Publisher:American Heart Association (U.S.A.)
Volume:110
Number:20
Page Range:3270-3275
Date:16 November 2004
Official Publication:https://doi.org/10.1161/01.CIR.0000147610.41984.E8
PubMed:View item in PubMed

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