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Vibration-synchronized magnetic resonance imaging for the detection of myocardial elasticity changes

Item Type:Article
Title:Vibration-synchronized magnetic resonance imaging for the detection of myocardial elasticity changes
Creators Name:Elgeti, T. and Tzschaetzsch, H. and Hirsch, S. and Krefting, D. and Klatt, D. and Niendorf, T. and Braun, J. and Sack, I.
Abstract:Vibration synchronized magnetic resonance imaging of harmonically oscillating tissue interfaces is proposed for cardiac magnetic resonance elastography. The new approach exploits cardiac triggered cine imaging synchronized with extrinsic harmonic stimulation (f = 22.83 Hz) to display oscillatory tissue deformations in magnitude images. Oscillations are analyzed by intensity threshold-based image processing to track wave amplitude variations over the cardiac cycle. In agreement to literature data, results in 10 volunteers showed that endocardial wave amplitudes during systole (0.13 ± 0.07 mm) were significantly lower than during diastole (0.34 ± 0.14 mm, P < 0.001). Wave amplitudes were found to decrease 117 ± 40 ms before myocardial contraction and to increase 75 ± 31 ms before myocardial relaxation. Vibration synchronized magnetic resonance imaging improves the temporal resolution of magnetic resonance elastography as it overcomes the use of extra motion encoding gradients, is less sensitive to susceptibility artifacts, and does not suffer from dynamic range constraints frequently encountered in phase-based magnetic resonance elastography.
Keywords:Time Harmonic Vibrations, Cardiac Elastography, MRE, Shear Modulus, Heart Contraction, Myocardial Relaxation, Shear Waves
Source:Magnetic Resonance in Medicine
Page Range:919-924
Date:April 2012
Official Publication:https://doi.org/10.1002/mrm.24185
PubMed:View item in PubMed

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