Thalamic control of cortical states

Item Type:	Article
Title:	Thalamic control of cortical states
Creators Name:	Poulet, J.F.A. and Fernandez, L.M.J. and Crochet, S. and Petersen, C.C.H.
Abstract:	We investigated the impact of thalamus on ongoing cortical activity in the awake, behaving mouse. We demonstrate that the desynchronized cortical state during active behavior is driven by a centrally generated increase in thalamic action potential firing, which can also be mimicked by optogenetic stimulation of the thalamus. The thalamus therefore is key in controlling cortical states.
Keywords:	Action Potentials, Afferent Pathways, Cortical Synchronization, Denervation, Electric Stimulation, Fourier Analysis, Neurons, Rhodopsin, Somatosensory Cortex, Transgenic Mice, Thalamus, Vibrissae, Wakefulness, Animals, Mice
Source:	Nature Neuroscience
ISSN:	1097-6256
Publisher:	Nature Publishing Group
Volume:	15
Number:	3
Page Range:	370-372
Date:	22 January 2012
Official Publication:	https://doi.org/10.1038/nn.3035
PubMed:	View item in PubMed

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