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An overview of the analysis of next generation sequencing data

Item Type:Article
Title:An overview of the analysis of next generation sequencing data
Creators Name:Gogol-Doering, A. and Chen, W.
Abstract:Next generation sequencing is a common and versatile tool for biological and medical research. We describe the basic steps for analyzing next generation sequencing data, including quality checking and mapping to a reference genome. We also explain the further data analysis for three common applications of next generation sequencing: variant detection, RNA-seq, and ChIP-seq.
Keywords:Next Generation Sequencing, Read Mapping, Variant Detection, RNA-seq, ChIP-seq , Animals
Source:Methods in Molecular Biology
Series Name:Methods in Molecular Biology
Title of Book:Next generation microarray bioinformatics : methods and protocols
ISSN:1064-3745
ISBN:978-1-61779-399-8
Publisher:Springer / Humana Press (U.S.A.)
Volume:802
Page Range:249-257
Number of Pages:401
Date:2012
Official Publication:https://doi.org/10.1007/978-1-61779-400-1_16
PubMed:View item in PubMed

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