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Heart development: mitochondria in command of cardiomyocyte differentiation

Official URL:https://doi.org/10.1016/j.devcel.2011.08.021
PubMed:View item in PubMed
Creators Name:Drenckhahn, J.D.
Journal Title:Developmental Cell
Journal Abbreviation:Dev Cell
Volume:21
Number:3
Page Range:392-393
Date:13 September 2011
Abstract:Continuous developmental maturation of cardiomyocytes is essential to meet the functional and metabolic demands of the growing heart. A new study (Hom et al., 2011) reports that embryonic cardiomyocytes are influenced by mitochondrial maturation, such that closure of the mitochondrial permeability transition pore results in decreased levels of reactive oxygen species, thereby inducing differentiation.
ISSN:1534-5807
Publisher:Cell Press (U.S.A.)
Item Type:Editorial

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