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Heart development: mitochondria in command of cardiomyocyte differentiation

Item Type:Editorial
Title:Heart development: mitochondria in command of cardiomyocyte differentiation
Creators Name:Drenckhahn, J.D.
Abstract:Continuous developmental maturation of cardiomyocytes is essential to meet the functional and metabolic demands of the growing heart. A new study (Hom et al., 2011) reports that embryonic cardiomyocytes are influenced by mitochondrial maturation, such that closure of the mitochondrial permeability transition pore results in decreased levels of reactive oxygen species, thereby inducing differentiation.
Source:Developmental Cell
ISSN:1534-5807
Publisher:Cell Press (U.S.A.)
Volume:21
Number:3
Page Range:392-393
Date:13 September 2011
Official Publication:https://doi.org/10.1016/j.devcel.2011.08.021
PubMed:View item in PubMed

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