Cellular conference call: external feedback affects cell-fate decisions

Item Type:	Editorial
Title:	Cellular conference call: external feedback affects cell-fate decisions
Creators Name:	Loewer, A. and Lahav, G.
Abstract:	Cells often need to respond to multiple opposing signals simultaneously. In this issue of Cell, it is shown that challenging cells with multiple extracellular signals induces an external feedback that involves the release of and response to additional secreted factors with antagonistic functions. These results suggest that an individual cell's decision to die or survive is not wholly independent but depends, at least in part, on feedback from its neighbors.
Keywords:	Apoptosis, Cell Survival, Epidermal Growth Factor, Physiological Feedback, Signal Transduction, Tumor Necrosis Factors, Animals
Source:	Cell
ISSN:	0092-8674
Publisher:	Cell Press
Volume:	124
Number:	6
Page Range:	1128-1130
Date:	24 March 2006
Official Publication:	https://doi.org/10.1016/j.cell.2006.03.010
PubMed:	View item in PubMed

Repository Staff Only: item control page