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Plasma folate, related genetic variants, and colorectal cancer risk in EPIC

Item Type:Article
Title:Plasma folate, related genetic variants, and colorectal cancer risk in EPIC
Creators Name:Eussen, S.J. and Vollset, S.E. and Igland, J. and Meyer, K. and Fredriksen, A. and Ueland, P.M. and Jenab, M. and Slimani, N. and Boffetta, P. and Overvad, K. and Tjonneland, A. and Olsen, A. and Clavel-Chapelon, F. and Boutron-Ruault, M.C. and Morois, S. and Weikert, C. and Pischon, T. and Linseisen, J. and Kaaks, R. and Trichopoulou, A. and Zilis, D. and Katsoulis, M. and Palli, D. and Berrino, F. and Vineis, P. and Tumino, R. and Panico, S. and Peeters, P.H. and Bueno-de-Mesquita, H.B. and van Duijnhoven, F.J. and Gram, I.T. and Skeie, G. and Lund, E. and Gonzalez, C.A. and Martinez, C. and Dorronsoro, M. and Ardanaz, E. and Navarro, C. and Rodriguez, L. and Van Guelpen, B. and Palmqvist, R. and Manjer, J. and Ericson, U. and Bingham, S. and Khaw, K.T. and Norat, T. and Riboli, E.
Abstract:A potential dual role of folate in colorectal cancer (CRC) is currently subject to debate. We investigate the associations between plasma folate, several relevant folate-related polymorphisms, and CRC risk within the large European Prospective Investigation into Cancer and Nutrition cohort.
Keywords:Case-Control Studies, Colorectal Neoplasms, Folic Acid, Genetic Predisposition to Disease, Methylenetetrahydrofolate Reductase (NADPH2), Single Nucleotide Polymorphism, Prognosis, Prospective Studies, Risk Factors, Survival Rate
Source:Cancer Epidemiology Biomarkers & Prevention
Publisher:American Association for Cancer Research
Page Range:1328-1340
Date:May 2010
Official Publication:https://doi.org/10.1158/1055-9965.EPI-09-0841
PubMed:View item in PubMed

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