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Takotsubo cardiomyopathy after nasal application of epinephrine--a magnetic resonance study

Item Type:Letter
Title:Takotsubo cardiomyopathy after nasal application of epinephrine--a magnetic resonance study
Creators Name:von Knobelsdorff-Brenkenhoff, F. and Abdel-Aty, H. and Schulz-Menger, J.
Abstract:Takotsubo cardiomyopathy (TTC), which is characterized by transient left ventricular impairment in absence of coronary artery disease, is usually associated with emotional or physical stress, supposing that catecholamines are involved in pathophysiology. The present article reports on two cases with characteristic features of TTC following nasal application of epinephrine during nasal surgery. Both subjects serially underwent cardiovascular magnetic resonance, which revealed myocardial vasodilatation, capillary leak and regional edema in the acute state and ruled out focal necrosis. Thus, the present cases both stress the catecholamine hypothesis in the pathogenesis of TTC and underline the potential of CMR to diagnose and monitor TTC.
Keywords:Cardiomyopathy, Magnetic Resonance Imaging, Catecholamines, Edema, Imaging
Source:International Journal of Cardiology
ISSN:0167-5273
Publisher:Elsevier (The Netherlands)
Volume:145
Number:2
Page Range:308-309
Date:19 November 2010
Official Publication:https://doi.org/10.1016/j.ijcard.2009.10.044
PubMed:View item in PubMed

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