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| Item Type: | Article |
|---|---|
| Title: | Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance |
| Creators Name: | Jarius, S. and Franciotta, D. and Paul, F. and Ruprecht, K. and Bergamaschi, R. and Rommer, P.S. and Reuss, R. and Probst, C. and Kristoferitsch, W. and Wandinger, K.P. and Wildemann, B. |
| Abstract: | In 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopathogenesis of NMO. |
| Keywords: | Aquaporin 4, Autoantibodies, Neuromyelitis Optica, Nonparametric Statistics, Sensitivity and Specificity |
| Source: | Journal of Neuroinflammation |
| ISSN: | 1742-2094 |
| Publisher: | BioMed Central |
| Volume: | 7 |
| Page Range: | 52 |
| Date: | 8 September 2010 |
| Official Publication: | https://doi.org/10.1186/1742-2094-7-52 |
| PubMed: | View item in PubMed |
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