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Cardiac chamber quantification using magnetic resonance imaging at 7 Tesla-a pilot study

Item Type:Article
Title:Cardiac chamber quantification using magnetic resonance imaging at 7 Tesla-a pilot study
Creators Name:von Knobelsdorff-Brenkenhoff, F. and Frauenrath, T. and Prothmann, M. and Dieringer, M.A. and Hezel, F. and Renz, W. and Kretschel, K. and Niendorf, T. and Schulz-Menger, J.
Abstract:OBJECTIVES: Interest in cardiovascular magnetic resonance (CMR) at 7 T is motivated by the expected increase in spatial and temporal resolution, but the method is technically challenging. We examined the feasibility of cardiac chamber quantification at 7 T. METHODS: A stack of short axes covering the left ventricle was obtained in nine healthy male volunteers. At 1.5 T, steady-state free precession (SSFP) and fast gradient echo (FGRE) cine imaging with 7 mm slice thickness (STH) were used. At 7 T, FGRE with 7 mm and 4 mm STH were applied. End-diastolic volume, end-systolic volume, ejection fraction and mass were calculated. RESULTS: All 7 T examinations provided excellent blood/myocardium contrast for all slice directions. No significant difference was found regarding ejection fraction and cardiac volumes between SSFP at 1.5 T and FGRE at 7 T, while volumes obtained from FGRE at 1.5 T were underestimated. Cardiac mass derived from FGRE at 1.5 and 7 T was larger than obtained from SSFP at 1.5 T. Agreement of volumes and mass between SSFP at 1.5 T and FGRE improved for FGRE at 7 T when combined with an STH reduction to 4 mm. CONCLUSIONS: This pilot study demonstrates that cardiac chamber quantification at 7 T using FGRE is feasible and agrees closely with SSFP at 1.5 T.
Keywords:Magnetic Resonance Imaging, Left Ventricle, Ultrahigh Field, Cardiac-Gated Imaging Techniques, Cine MRI
Source:European Radiology
Page Range:2844-2852
Date:December 2010
Official Publication:https://doi.org/10.1007/s00330-010-1888-2
PubMed:View item in PubMed

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