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The dangers of transcription

Official URL:https://doi.org/10.1016/j.cell.2009.11.037
PubMed:View item in PubMed
Creators Name:Mathas, S. and Misteli, T.
Journal Title:Cell
Journal Abbreviation:Cell
Volume:139
Number:6
Page Range:1047-1049
Date:11 December 2009
Keywords:Double-Stranded DNA Breaks, Neoplastic Gene Expression Regulation, Androgen Receptors, Genetic Translocation
Abstract:Transcription is obviously essential, but even a good thing can be dangerous at times. In this issue, Lin et al. (2009) provide evidence that binding of the transcription machinery may predispose genome regions to breakage and translocations that may lead to cancer.
ISSN:0092-8674
Publisher:Cell Press (U.S.A.)
Item Type:Editorial

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