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The dangers of transcription

Item Type:Editorial
Title:The dangers of transcription
Creators Name:Mathas, S. and Misteli, T.
Abstract:Transcription is obviously essential, but even a good thing can be dangerous at times. In this issue, Lin et al. (2009) provide evidence that binding of the transcription machinery may predispose genome regions to breakage and translocations that may lead to cancer.
Keywords:Double-Stranded DNA Breaks, Neoplastic Gene Expression Regulation, Androgen Receptors, Genetic Translocation
Source:Cell
ISSN:0092-8674
Publisher:Cell Press (U.S.A.)
Volume:139
Number:6
Page Range:1047-1049
Date:11 December 2009
Official Publication:https://doi.org/10.1016/j.cell.2009.11.037
PubMed:View item in PubMed

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