Browse by Research Area

2025

Carbon-based nanostructure drug delivery systems and their biologic applications – a review.
Alvandi, H., Shafie, A., Najafi, F., Sabzini, M., Mashayekhi, M., Omami, S.H., Eskandarisani, M.M., Dashti, S., Javanmard, A., Tajik, M., Bräse, S. and Farmani, A.R.
Carbon Letters 8 June 2025 (In Press)

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A.
Brierley, C.K., Yip, B.H., Orlando, G., Wen, J., Wen, S., Goyal, H., Levine, M., Jakobsdottir, G.M., Tapinos, A., Cornish, A.J., Rodriguez-Romera, A., Rodriguez-Meira, A., Bashton, M., Hamblin, A., Clark, S.A., Hamley, J.C., Fox, O., Giurgiu, M., O'Sullivan, J., Murphy, L., Adamo, A., Olijnik, A.A., Cotton, A., Hendrix, E., Narina, S., Pruett-Miller, S.M., Enshaei, A., Harrison, C., Drummond, M., Knapper, S., Tefferi, A., Antony-Debré, I., Davies, J., Henssen, A.G., Thongjuea, S., Wedge, D.C., Constantinescu, S.N., Papaemmanuil, E., Psaila, B., Crispino, J.D. and Mead, A.J.
Nature Genetics 57 (6): 1478-1492. June 2025

Neurodevelopmental origins of structural and psychomotor defects in CXCR4-linked primary immunodeficiency.
Demenego, G., Mancinelli, S., Borreca, A., Proce, R.O., Aragona, V., Miotto, M., Cremonesi, M., Zucchelli, L., Corradini, I., Kim, E., Ilic, K., Fraviga, E., Pellegrino, L., Badolato, R., Rusconi, R., Pozzi, D., Kallikourdis, M., Cash, D., Matteoli, M. and Lodato, S.
Neuron 6 June 2025 (In Press)

Chemical targeting of the ATXN1 aa99–163 interaction site suppresses polyQ-expanded protein dimerization.
Gkekas, I., Pliatsika, K., Mylonas, S., Katsamakas, S., Axenopoulos, A., Kostova, S., Wanker, E.E., Hadjipavlou-Litina, D., Xanthopoulos, K., Daras, P. and Petrakis, S.
ACS Omega 10 (25): 27194-27205. 1 July 2025

The postbiotic ReFerm versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial.
Hansen, J.K., Israelsen, M., Nishijima, S., Stinson, S.E., Andersen, P., Johansen, S., Hansen, C.D., Brol, M.J., Klein, S., Schierwagen, R., Uschner, F.E., Sulek, K., Villesen, I.F., Lindvig, K.P., Thorhauge, K.H., Torp, N., Jensen, J.M., Keller, M.I., Jensen, G.H., Detlefsen, S., Leeming, D.J., Stankevic, E., Suvitaival, T., Zawadzki, A., Kuhn, M., Jensen, L.J., Karsdal, M., Trebicka, J., Israelsen, H., Legido-Quigley, C., Bork, P., Arumugam, M., Hansen, T., Thiele, M. and Krag, A.
Nature Communications 16 (1): 5969. 1 July 2025

Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference.
Heyn, J.C.J., Atienza Juanatey, M., Falcke, M. and Rädler, J.O.
PLoS ONE 20 (6): e0310669. 18 June 2025

CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis.
Jerke, U., Eulenberg-Gustavus, C., Wagner, D.L., Schreiber, A. and Kettritz, R.
Kidney International 108 (1): 145-149. July 2025

Endogenous SNAP-tagging of Munc13-1 for monitoring synapse nanoarchitecture.
Kowald, M., Bachollet, S.P.J.T., Benseler, F., Steinecker, M., Boll, M., Kaushik, S., Soykan, T., Sun, S., Birke, R., Ilic, D., Brose, N., Hörnberg, H., Lehmann, M., Rizzoli, S.O., Broichhagen, J. and Lipstein, N.
JACS Au 5 (6): 2475-2490. 23 June 2025

Spermidine supplementation and protein restriction protect from organismal and brain aging independently.
Liang, Y.T., Krivograd, A., Hofer, S.J., Kollipara, L., Züllig, T., Sickmann, A., Eisenberg, T. and Sigrist, S.J.
Aging 17 7 June 2025 (In Press)

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.
Mobach, S., Bergkamp, N.D., Ma, Z., Haselager, M.V., Anbuhl, S.M., Jurriens, D., van den Bor, J., Wang, Z., Crudden, C., Roos, J.L., Perez Almeria, C.V., Boergonje, R.A., Lohse, M.J., Bosma, R., Eldering, E., Siderius, M., Wu, W., Spaargaren, M., Tonino, S.H., Kater, A.P., Smit, M.J. and Heukers, R.
Proceedings of the National Academy of Sciences of the United States of America 122 (24): e2424186122. 17 June 2025

Accurate prediction of ecDNA in interphase cancer cells using deep neural networks.
Rajkumar, U., Prasad, G., Curtis, E.J., Wong, I.T.L., Yan, X., Zhang, S., Brückner, L., Turner, K., Wiese, J., Wahl, J., Wu, S., Theissen, J., Fischer, M., Chang, H.Y., Henssen, A.G., Mischel, P.S. and Bafna, V.
bioRxiv : 2025.06.23.661188. 27 June 2025

MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor.
Sohai, I., Laurin, S.A., Kleinau, G., Chunilal, V., Morton, A., Brenlla-Lopez, A., Kagiali, Z.C.U., Tello, J.A., Beck-Sickinger, A.G., Blouin, M.J., Lohse, M.J., Scheerer, P., Bouvier, M., McCormick, P., Annibale, P. and Biebermann, H.
bioRxiv : 2024.04.09.588099v4. 4 June 2025