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Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
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Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors.
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Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.
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Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism.
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Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.
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Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.
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