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Novel tetrazolo-pyridazine-based MACC1 transcriptional inhibitor reduces NFκb signaling pathway as key antimetastatic mechanism of action.
Schöpe, Paul Curtis ORCID: https://orcid.org/0000-0002-5512-8832, Dahlmann, Mathias ORCID: https://orcid.org/0000-0002-0036-5283, Kobelt, Dennis ORCID: https://orcid.org/0000-0002-9373-0648, Gohlke, Bjoern-O, Shoman, Abdelrhman M. ORCID: https://orcid.org/0009-0005-4991-6209, Walther, Wolfgang ORCID: https://orcid.org/0000-0003-2884-0231, Preissner, Robert ORCID: https://orcid.org/0000-0002-2407-1087, Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330 and Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X
Journal of Biotechnology and Biomedicine 8 (4): 356-369. 30 December 2025