Article

Spermidine mitigates immune cell senescence and boosts vaccine responses in healthy older adults -- a pilot study.
Alsaleh, Ghada, Ali, Mohammad ORCID: https://orcid.org/0000-0003-0170-7182, Kayvanjoo, Amir Hossein ORCID: https://orcid.org/0000-0003-1315-8336, Liu, Feng, Moreau, Tanaïs, Bibi, Sagida, Luo, Lin, Govender, Melissa, Carroll, Miles, Hofer, Sebastian J., Tobias, Eisenberg, Magnes, Christoph, Kell, Loren ORCID: https://orcid.org/0000-0003-1322-2027, Chung, Christopher, Deng, Yu, Bhandari, Aneesha, Garner, Lucy ORCID: https://orcid.org/0000-0002-6461-252X, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Chen, Liye, Kronsteiner-Dobramysl, Barbara, Dunachie, Susie, Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Lambe, Teresa, Klenerman, Paul, Jones, Lucy C. and Simon, A. Katharina ORCID: https://orcid.org/0000-0002-4077-7995
Aging Cell 25 (6): e70545. June 2026

Rapamycin exerts its geroprotective effects in the ageing human immune system by enhancing resilience against DNA damage.
Kell, Loren ORCID: https://orcid.org/0000-0003-1322-2027, Jones, Eleanor J. ORCID: https://orcid.org/0000-0003-3261-3787, Gharahdaghi, Nima ORCID: https://orcid.org/0000-0002-4650-244X, Wilkinson, Daniel J. ORCID: https://orcid.org/0000-0001-8808-8243, Smith, Kenneth ORCID: https://orcid.org/0000-0001-8971-6635, Atherton, Philip J. ORCID: https://orcid.org/0000-0002-7286-046X, Simon, Anna K. ORCID: https://orcid.org/0000-0002-4077-7995, Cox, Lynne S. ORCID: https://orcid.org/0000-0002-5306-285X and Alsaleh, Ghada ORCID: https://orcid.org/0000-0002-4211-3420
Aging Cell 25 (2): e70364. February 2026

Age attenuates the T-type Ca(V) 3.2-RyR axis in vascular smooth muscle.
Fan, G. ORCID: https://orcid.org/0000-0003-1894-3253, Kaßmann, M. ORCID: https://orcid.org/0000-0002-4785-6530, Cui, Y., Matthaeus, C. ORCID: https://orcid.org/0000-0003-3242-1195, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Zhong, C., Zhu, S., Xie, Yu, Tsvetkov, D. ORCID: https://orcid.org/0000-0002-6472-971X, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Huang, Yu and Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934
Aging Cell 19 (4): e13134. April 2020

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, He, M., Krause, A. ORCID: https://orcid.org/0000-0001-9515-2477, Vitrinel, B. ORCID: https://orcid.org/0000-0002-5049-6572, Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629
Aging Cell 18 (6): e13012. December 2019

In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Sanderson, S.L. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Aging Cell 16 (6): 1234-1243. December 2017

Mitochondrial DNA deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins.
Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952 and Cortopassi, G.
Aging Cell 6 (5): 619-630. October 2007

Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus.
Garcia, A., Steiner, B., Kronenberg, G. ORCID: https://orcid.org/0000-0002-5310-9849, Bick-Sander, A. and Kempermann, G. ORCID: https://orcid.org/0000-0002-5304-4061
Aging Cell 3 (6): 363-371. 1 December 2004

Review

Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells.
Zhou, D., Borsa, M. ORCID: https://orcid.org/0000-0003-1519-2597 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Aging Cell 20 (2): e13316. 1 February 2021