Browse by Research Team

2009

Identification of brain- and bone-specific breast cancer metastasis genes.
Klein, A. and Olendrowitz, C. and Schmutzler, R. and Hampl, J. and Schlag, P.M. and Maass, N. and Arnold, N. and Wessel, R. and Ramser, J. and Meindl, A. and Scherneck, S. and Seitz, S.
Cancer Letters 276 (2): 212-220. 18 April 2009

Decreased expression of angiogenesis antagonist EFEMP1 in sporadic breast cancer is caused by aberrant promoter methylation and points to an impact of EFEMP1 as molecular biomarker.
Sadr-Nabavi, A. and Ramser, J. and Volkmann, J. and Naehrig, J. and Wiesmann, F. and Betz, B. and Hellebrand, H. and Engert, S. and Seitz, S. and Kreutzfeld, R. and Sasaki, T. and Arnold, N. and Schmutzler, R. and Kiechle, M. and Niederacher, D. and Harbeck, N. and Dahl, E. and Meindl, A.
International Journal of Cancer 124 (7): 1727-1735. 1 April 2009

2007

Suppression of polyploidy by the BRCA2 protein.
Sagulenko, E. and Savelyeva, L. and Ehemann, V. and Sagulenko, V. and Hofmann, W. and Arnold, K. and Claas, A. and Scherneck, S. and Schwab, M.
Cancer Letters 257 (1): 65-72. 8 November 2007

Comparison of gene expression data from human and mouse breast cancers: identification of a conserved breast tumor gene set.
Klein, A. and Wessel, R. and Graessmann, M. and Juergens, M. and Petersen, I. and Schmutzler, R. and Niederacher, D. and Arnold, N. and Meindl, A. and Scherneck, S. and Seitz, S. and Graessmann, A.
International Journal of Cancer 121 (3): 683-688. 1 August 2007

Hamster polyomavirus-derived virus-like particles are able to transfer in vitro encapsidated plasmid DNA to mammalian cells.
Voronkova, T. and Kazaks, A. and Ose, V. and Oezel, M. and Scherneck, S. and Pumpens, P. and Ulrich, R.
Virus Genes 34 (3): 303-314. June 2007

Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway.
Wenzel, K. and Daskalow, K. and Herse, F. and Seitz, S. and Zacharias, U. and Schenk, J.A. and Schulz, H. and Huebner, N. and Micheel, B. and Schlag, P.M. and Osterziel, K.J. and Ozcelik, C. and Scherneck, S. and Jandrig, B.
Biological Chemistry 388 (5): 489-495. May 2007

2006

Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression.
Seitz, S. and Korsching, E. and Weimer, J. and Jacobsen, A. and Arnold, N. and Meindl, A. and Arnold, W. and Gustavus, D. and Klebig, C. and Petersen, I. and Scherneck, S.
Genes Chromosomes & Cancer 45 (6): 612-627. June 2006

2005

Profile of differentially expressed genes after transfer of chromosome 17 into the breast cancer cell line CAl51.
Klebig, C. and Seitz, S. and Korsching, E. and Kristiansen, G. and Gustavus, D. and Scherneck, S. and Petersen, I.
Genes Chromosomes & Cancer 44 (3): 233-246. 27 July 2005

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype.
Lakhani, S.R. and Reis-Filho, J.S. and Fulford, L. and Penault-Llorca, F. and van der Vjiver, M. and Parry, S. and Bishop, T. and Benitez, J. and Rivas, C. and Bignon, Y.J. and Chang-Claude, J. and Hamann, U. and Cornelisse, C.J. and Devilee, P. and Beckmann, M.W. and Nestle-Kramling, C. and Daly, P.A. and Haites, N. and Varley, J. and Lalloo, F. and Evans, G. and Maugard, C. and Meijers-Heijboer, H. and Klijn, J.G.M. and Olah, E. and Gusterson, B.A. and Pilotti, S. and Radice, P. and Scherneck, S. and Sobol, H. and Jacquemier, J. and Wagner, T. and Peto, J. and Stratton, M.R. and McGuffog, L. and Easton, D.F.
Clinical Cancer Research 11 (14): 5175-5180. 15 July 2005

A network of clinically and functionally relevant genes is involved in the reversion of the tumorigenic phenotype of MDA-MB-231 breast cancer cells after transfer of human chromosome 8.
Seitz, S. and Frege, R. and Jacobsen, A. and Weimer, J. and Arnold, W. and Haefen, C.v. and Niederacher, D. and Schmutzler, R. and Arnold, N. and Scherneck, S.
Oncogene 24 (5): 869-879. 1 January 2005

Characterization of gamma-aminobutyric acid type A receptor associated protein, a novel tumor suppressor, showing reduced expression in breast cancer.
Klebig, C. and Seitz, S. and Arnold, W. and Deutschmann, N. and Pacyna-Gengelbach, M. and Scherneck, S. and Petersen, I.
Cancer Research 65 : 394-400. 1 January 2005

Characterization of the human P-type 6-phosphofructo-1-kinase gene promoter in neural cell lines.
Hannemann, A. and Jandrig, B. and Gaunitz, F. and Eschrich, K. and Bigl, M.
Gene 345 (2): 237-247. 1 January 2005

Mutation analysis of BRCA1 and BRCA2 genes in Iranian high risk breast cancer families.
Pietschmann, A. and Mehdipour, P. and Mehdipour, P. and Atri, M. and Hofmann, W. and Hosseini-Asl, S. and Scherneck, S. and Mundlos, S. and Peters, H.
Journal of Cancer Research and Clinical Oncology 131 (8): 552-558. 1 January 2005

Nucleocapsid protein of cell culture-adapted Seoul virus strain 80-39: Analysis of its encoding sequence, expression in yeast and immuno-reactivity.
Schmidt, J. and Jandrig, B. and Klempa, B. and Yoshimatsu, K. and Arikawa, J. and Meisel, H. and Niedrig, M. and Pitra, C. and Krueger, D.H. and Ulrich, R.
Virus Genes 30 (1): 37-48. 1 January 2005

Brustkrebs bei Frauen mit Down-Syndrom.
Scherneck, S. and Jandrig, B.
Leben mit Down-Syndrom 50 : 38-39. 2005

2004

ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.
Jandrig, B. and Seitz, S. and Hinzmann, B. and Arnold, W. and Micheel, B. and Koelble, K. and Siebert, R. and Schwartz, A. and Ruecker, K. and Schlag, P.M. and Scherneck, S. and Rosenthal, A.
Oncogene 23 (57): 9295-9302. 18 October 2004

Detection of cell-free DNA in bronchial lavage fluid supernatants of patients with lung cancer.
Carstensen, T. and Schmidt, B. and Engel, E. and Jandrig, B. and Witt, C. and Fleischhacker, M.
Annals of the New York Academy of Sciences 1022 : 202-210. 1 June 2004

Detection of tumor-specific mRNA in cell-free bronchial lavage supernatant in patients with lung cancer.
Engel, E. and Schmidt, B. and Carstensen, T. and Weickmann, S. and Jandrig, B. and Witt, C. and Fleischhacker, M.
Annals of the New York Academy of Sciences 1022 : 140-146. 1 June 2004

Pathology of ovarian cancers in BRCA1 and BRCA2 carriers.
Lakhani, S.R. and Manek, S. and Penault-Llorca, F. and Flanagan, A. and Arnout, L. and Merrett, S. and McGuffog, L. and Steele, D. and Devilee, P. and Klijn, J.G. and Meijers-Heijboer, H. and Radice, P. and Pilotti, S. and Nevanlinna, H. and Butzow, R. and Sobol, H. and Jacquemier, J. and Lyonet, D.S. and Neuhausen, S.L. and Weber, B. and Wagner, T. and Winqvist, R. and Bignon, Y.J. and Monti, F. and Schmitt, F. and Lenoir, G. and Seitz, S. and Hamman, U. and Pharoah, P. and Lane, G. and Ponder, B. and Bishop, D.T. and Easton, D.F.
Clinical Cancer Research 10 (7): 2473-2481. 1 April 2004

Tumor suppressor activity of profilin requires a functional actin binding site.
Wittenmayer, N. and Jandrig, B. and Rothkegel, M. and Schlueter, K. and Arnold, W. and Haensch, W. and Scherneck, S. and Jockusch, B.M.
Molecular Biology of the Cell 15 (4): 1600-1608. April 2004

Detection of cell-free nucleic acids in bronchial lavage fluid supernatants from patients with lung cancer.
Schmidt, B. and Carstensen, T. and Engel, E. and Jandrig, B. and Witt, C. and Fleischhacker, M.
European Journal of Cancer 40 (3): 452-460. February 2004

Limited relevance of the CHEK2 gene in hereditary breast cancer.
Dufault, M.R. and Betz, B. and Wappenschmidt, B. and Hofmann, W. and Bandick, K. and Golla, A. and Pietschmann, A. and Nestle-Kraemling, C. and Rhiem, K. and Huettner, C. and von Lindern, C. and Dall, P. and Kiechle, M. and Untch, M. and Jonat, W. and Meindl, A. and Scherneck, S. and Niederacher, D. and Schmutzler, R.K. and Arnold, N.
International Journal of Cancer 110 (3): 320-325. 1 January 2004

2003

Distinct methylation profiles of glioma subtypes.
Uhlmann, K. and Rohde, K. and Zeller, C. and Szymas, J. and Vogel, S. and Marczinek, K. and Thiel, G. and Nuernberg, P. and Laird, P.W.
International Journal of Cancer 106 (1): 52-59. 10 August 2003

Screening for large rearrangements of the BRCA1 gene in German breast or ovarian cancer families using semi-quantitative multiplex PCR method.
Hofmann, W. and Goergens, H. and John, A. and Horn, D. and Huettner, C. and Arnold, N. and Scherneck, S. and Schackert, H.K.
Human Mutation 22 (1): 103-104. 1 July 2003

Analysis of DLC-1 expression in human breast cancer.
Plaumann, M. and Seitz, S. and Frege, R. and Estevez-Schwarz, L. and Scherneck, S.
Journal of Cancer Research and Clinical Oncology 129 (6): 349-354. June 2003

SASH1: a candidate tumor suppressor gene on chromosome 6q24.3 is downregulated in breast cancer.
Zeller, C. and Hinzmann, B. and Seitz, S. and Prokoph, H. and Burkhard-Goettges, E. and Fischer, J. and Jandrig, B. and Schwarz, L.E. and Rosenthal, A. and Scherneck, S.
Oncogene 22 (19): 2972-2983. 15 May 2003

Identification and characterization of KAT, a novel gene preferentially expressed in several human cancer cell lines.
Wenzel, K. and Felix, S.B. and Flachmeier, C. and Heere, P. and Schulze, W. and Grunewald, I. and Pankow, H. and Hewelt, A. and Scherneck, S. and Bauer, D. and Hoehe, M.R.
Biological Chemistry 384 (5): 763-775. 1 May 2003

Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.
Seitz, S. and Wassmuth, P. and Plaschke, J. and Schackert, H.K. and Karsten, U. and Santibanez-Koref, M.F. and Schlag, P.M. and Scherneck, S.
Genes Chromosomes & Cancer 37 (1): 29-35. May 2003

The BRCA2 variant 8204G>A is a splicing mutation and results in an in frame deletion of the gene.
Hofmann, W. and Horn, D. and Huettner, C. and Classen, E. and Scherneck, S.
Journal of Medical Genetics 40 : e23. 1 March 2003

Role of LDL receptor-related protein (LRP) in coronary atherosclerosis.
Schulz, S. and Birkenmeier, G. and Schagdarsurengin, U. and Wenzel, K. and Mueller-Werdan, U. and Rehfeld, D. and Suess, T. and Kabisch, A. and Werdan, K. and Glaeser, C.
International Journal of Cardiology 92 (2-3): 137-144. 1 January 2003

2002

Mutation analysis and mRNA expression of trail-receptors in human breast cancer.
Seitz, S. and Wassmuth, P. and Fischer, J. and Nothnagel, A. and Jandrig, B. and Schlag, P.M. and Scherneck, S.
International Journal of Cancer 102 (2): 117-128. 10 November 2002

Cancer Incidence in BRCA1 mutation carriers.
Thompson, D. and Easton, D.F. and Scherneck, S. and Seitz, S.
Journal of the National Cancer Institute 94 (18): 1358-1365. 18 September 2002

Pigmentary mosaicism of the hyperpigmented type in two half-brothers.
Horn, D. and Happle, R. and Neitzel, H. and Kunze, J.
American Journal of Medical Genetics 112 (1): 65-69. 15 September 2002

Familial interstitial 570 kbp deletion of the UBE3A gene region causing Angelman syndrome but not Prader-Willi syndrome.
Buerger, J. and Horn, D. and Toennies, H. and Neitzel, H. and Reis, A.
American Journal of Medical Genetics A 111 (3): 233-237. 15 August 2002

Polyomavirus infection in hamsters and trichoepitheliomas/cutaneous adnexal tumours.
Foster, A.P. and Brown, P.J. and Jandrig, B. and Grosch, A. and Voronkova, T. and Scherneck, S. and Ulrich, R.
Veterinary Record 151 : 13-17. 6 July 2002

Detection of large rearrangements of exons 13 and 22 in the BRCA1 gene in German families.
Hofmann, W. and Wappenschmidt, B. and Berhane, S. and Schmutzler, R. and Scherneck, S.
Journal of Medical Genetics 39 : E36. 1 July 2002

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.
Lakhani, S.R. and Van de Vijver, M.J. and Jacquemier, J. and Anderson, T.J. and Osin, P.P. and McGuffog, L. and Easton, D.F. and Scherneck, S. and Seitz, S.
Journal of Clinical Oncology 20 (9): 2310-2318. 1 May 2002

Variation in BRCA1 cancer risks by mutation position.
Thompson, D. and Easton, D. and Scherneck, S. and Seitz, S.
Cancer Epidemiology Biomarkers & Prevention 11 : 329-336. April 2002

Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population.
Meindl, A.
International Journal of Cancer 97 : 472-480. 1 February 2002

A competitive immunoassay to detect a hapten using an enzyme-labelled peptide mimotope as tracer.
Sellrie, F. and Schenk, J.A. and Behrsing, O. and Boettger, V. and Micheel, B.
Journal of Immunological Methods 261 (1-2): 141-144. 1 January 2002

Chimeric bacteriophage fr virus-like particles harboring the immunodominant C-terminal region of hamster polyomavirus VP1 induce a strong VP1-specific antibody response in rabbits and mice.
Voronkova, T. and Grosch, A. and Kazaks, A. and Ose, V. and Skrastina, D. and Sasnauskas, K. and Jandrig, B. and Arnold, W. and Scherneck, S. and Pumpens, P. and Ulrich, R.
Viral Immunology 15 (4): 627-643. 2002

Genetische Alterationen und tumorassoziierte Gene.
Jandrig, B. and Scherneck, S.
In: Molekulare Medizin in der Frauenheilkunde : Diagnostik und Therapie. Steinkopff, Darmstadt, 21-30. ISBN 3-7985-1301-5 2002

Two hybrid cDNA cloning.
Schenk, J.A.
In: Genetic Library Construction and Screening. Springer, Berlin, 145-165. ISBN 978-3-642-47733-1 2002

2001

Detection of amplifiable messenger RNA in the serum of patients with lung cancer.
Fleischhacker, M. and Beinert, T. and Ermitsch, M. and Seferi, D. and Possinger, K. and Engelmann, C. and Jandrig, B.
Annals of the New York Academy of Sciences 945 : 179-188. September 2001

Anauxetic dysplasia, a spondylometaepiphyseal dysplasia with extreme dwarfism.
Horn, D. and Rupprecht, E. and Kunze, J. and Spranger, J.
Journal of Medical Genetics 38 : 262-265. 1 January 2001

Constitutional genomic instability with inversions, duplications, and amplifications in 9p23-24 in BRCA2 mutation carriers.
Savelyeva, L. and Claas, A. and Matzner, I. and Schlag, P.M. and Hofmann, W. and Scherneck, S. and Weber, B. and Schwab, M.
Cancer Research 61 : 5179-5185. 1 January 2001

Detailed deletion mapping in sporadic breast cancer at chromosomal region 17p13 distal to the TP53 gene: association with clinicopathological parameters.
Seitz, S. and Poppe, K. and Fischer, J. and Nothnagel, A. and Estevez-Schwarz, L. and Haensch, W. and Schlag, P.M. and Scherneck, S.
Journal of Pathology 194 (3): 318-326. 1 January 2001

Identification of a recurrent BRCA1 mutation in German breast-cancer and/or ovarian-cancer families.
Hofmann, W. and Jandrig, B. and Classen, E. and Nestle-Kraemling, C. and Chang-Claude, J. and Scherneck, S.
Journal of Cancer Research and Clinical Oncology 127 (3): 200-202. 1 January 2001

Prenatal diagnosis in Coffin-Lowry syndrome demonstrates germinal mosaicism confirmed by mutation analysis.
Horn, D. and Delaunoy, J.P. and Kunze, J.
Prenatal Diagnosis 21 : 881-884. 1 January 2001

The hamster polyomavirus - a brief review of recent knowledge.
Scherneck, S. and Ulrich, R. and Feunteun, J.
Virus Genes 22 (1): 93-101. 1 January 2001

2000

BRCA1 and BRCA2 - breast cancer susceptibility genes.
Hofmann, W. and Schlag, P.M.
Journal of Cancer Research and Clinical Oncology 126 (9): 487-496. 1 September 2000

Refined deletion mapping in sporadic breast cancer at chromosomal region 8p12-p21 and association with clinicopathological parameters.
Seitz, S. and Werner, S. and Fischer, J. and Nothnagel, A. and Schlag, P.M. and Scherneck, S.
European Journal of Cancer 36 (12): 1507-1513. 1 August 2000

Formation of immunogenic virus-like particles by inserting epitopes into surface-exposed regions of hamster polyomavirus major capsid protein.
Gedvilaite, A. and Froemmel, C. and Sasnauskas, K. and Micheel, B. and Oezel, M. and Behrsing, O. and Staniulis, J. and Jandrig, B. and Scherneck, S. and Ulrich, R.
Virology 273 (1): 21-35. 20 July 2000

Effect of the size of the deletion and clinical manifestation in Wolf-Hirschhorn syndrome: analysis of 13 patients with a de novo deletion.
Wieczorek, D. and Krause, M. and Majewski, F. and Albrecht, B. and Horn, D. and Riess, O. and Gillessen-Kaesbach, G.
European Journal of Human Genetics 8 (7): 519-526. July 2000

Homozygosity mapping in a family with microcephaly, mental retardation, and short stature to a Cohen syndrome region on 8q21.3-8q22.1: Redefining a clinical entity.
Horn, D. and Krebsova, A. and Kunze, J. and Reis, A.
American Journal of Medical Genetics 92 (4): 285-292. 5 June 2000

A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions.
Jenne, D.E. and Tinschert, S. and Stegmann, E. and Reimann, H. and Nuernberg, P. and Horn, D. and Naumann, I. and Buske, A. and Thiel, G.
Genomics 66 : 93-97. 15 May 2000

Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1.
Janke, J. and Schlueter, K. and Jandrig, B. and Theile, M. and Koelble, K. and Arnold, W. and Grinstein, E. and Schwartz, A. and Estevez-Schwarz, L. and Schlag, P.M. and Jockusch, B.M. and Scherneck, S.
Journal of Experimental Medicine 191 (10): 1675-1685. 15 May 2000

Detection of microsatellite alterations in the DNA isolated from tumor cells and from plasma DNA of patients with lung cancer.
Bruhn, N. and Beinert, T. and Oehm, C. and Jandrig, B. and Petersen, I. and Chen, X.Q. and Possinger, K. and Fleischhacker, M.
Annals of the New York Academy of Sciences 906 : 72-82. April 2000

Feasibility of simultaneous fluorescence immunophenotyping and fluorescence in situ hybridization study for the detection of estrogen receptor expression and deletions of the estrogen receptor gene in breast carcinoma cell lines.
Zhang, Y.M. and Siebert, R. and Matthiesen, P. and Harder, S. and Theile, M. and Scherneck, S. and Schlegelberger, B.
Virchows Archiv 436 (3): 271-275. 1 March 2000

The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2.
Lakhani, S.R. and Gusterson, B.A. and Jacquemier, J. and Sloane, J.P. and Anderson, T.J. and Van de Vijver, M.J. and Venter, D. and Freeman, A. and Antoniou, A. and McGuffog, L. and Smyth, E. and Steel, C.M. and Haites, N. and Scott, R.J. and Goldgar, D. and Neuhausen, S. and Daly, P.A. and Ormiston, W. and McManus, R. and Scherneck, S. and Ponder, B.A.J. and Futreal, P.A. and Peto, J. and Stoppa-Lyonnet, D. and Bignon, Y.J. and Struewing, J.P. and Bishop, D.T. and Klijn, J.G.M. and Devilee, P. and Cornelisse, C.J. and Lasset, C. and Lenoir, G. and Barkardottir, R.B. and Egilsson, V. and Hamann, U. and Chang-Claude, J. and Sobol, H. and Weber, B. and Easton, D.F. and Stratton, M.R.
Clinical Cancer Research 6 (3): 782-789. March 2000

An immunodominant, cross-reactive B-cell epitope region is located at the C-terminal part of the hamster polyomavirus major capsid protein VP1.
Siray, H. and Frommel, C. and Voronkova, T. and Hahn, S. and Arnold, W. and Schneider-Mergener, J. and Scherneck, S. and Ulrich, R.
Viral Immunology 13 (4): 533-545. 2000

1999

Mutations in exons 5-8 of the p53 gene, independent of their type and location, are associated with increased apoptosis and mitosis in invasive breast carcinoma.
Van Slooten, H.J. and Van de Vijver, M.J. and Borresen, A.L. and Eyfjord, J.E. and Valgardsdottir, R. and Scherneck, S. and Nesland, J.M. and Devilee, P. and Cornelisse, C.J. and Van Dierendonck, J.H.
Journal of Pathology 189 (4): 504-513. December 1999

Microsatellite alterations in serum DNA of patients with colorectal cancer.
Koelble, K. and Ullrich, O.M. and Pidde, H. and Barthel, B. and Diermann, J. and Rudolph, B. and Dietel, M. and Schlag, P.M. and Scherneck, S.
Laboratory Investigation 79 : 1145-1150. 1 September 1999

Two regions of deletion in 9p23-24 in sporadic breast cancer.
An, H.X. and Claas, A. and Savelyeva, L. and Seitz, S. and Schlag, P.M. and Scherneck, S. and Schwab, M.
Cancer Research 59 : 3941-3943. 15 August 1999

Loss of heterozygosity at 11q23.1 and survival in breast cancer: Results of a large European study.
Laake, K. and Launonen, V. and Niederacher, D. and Gudlaugsdottir, S. and Seitz, S. and Rio, P. and Champeme, M.H. and Bieche, I. and Birnbaum, D. and White, G. and Sztan, M. and Sever, N. and Plummer, S. and Osorio, A. and Broeks, A. and Huusko, P. and Spurr, N. and Borg, A. and Cleton-Jansen, A.M. and Veer, L. and Benitez, J. and Casey, G. and Peterlin, B. and Olah, E. and Varley, J. and Bignon, Y.J. and Scherneck, S. and Sigurdardottir, V. and Lidereau, R. and Eyfjord, J. and Beckmann, M.W. and Winqvist, R. and Skovlund, E. and Borresen-Dale, A.L.
Genes Chromosomes & Cancer 25 : 212-221. 1 July 1999

Verfahren zur Gewinnung von virusaehnlichen Partikeln auf der Basis von Polyomaviren [Method for producing virus-like particles on the basis of polyoma viruses].
Scherneck, S. and Sasnauskas, K. and Ulrich, R.
DE19750220A1 ; EP1030923. 20 May 1999

European multicenter study on LOH of APOC3 at 11q23 in 766 breast cancer patients: relation to clinical variables.
Launonen, V. and Laake, K. and Huusko, P. and Niederacher, D. and Beckmann, M.W. and Barkardottir, R.B. and Geirsdottir, E.K. and Gudmundsson, J. and Rio, P. and Bignon, Y.J. and Seitz, S. and Scherneck, S. and Bieche, I. and Champeme, M.H. and Birnbaum, D. and White, G. and Varley, J. and Sztan, M. and Olah, E. and Osorio, A. and Benitez, J. and Spurr, N. and Velikonja, N. and Peterlin, B. and Borg, A. and Cleton-Jansen, A.M. and Devilee, P. and Bloigu, R. and Lidereau, R. and Borresen-Dale, A.L. and Winqvist, R.
British Journal of Cancer 80 : 879-882. 1 May 1999

BRCA1 und BRCA2: Mutationen und andere genetische Veraenderungen - praktische Relevanz.
Scherneck, S. and Hofmann, W.
Chirurg 70 : 373-379. 1 April 1999

Yeast cells allow high-level expression and formation of polyomavirus-like particles.
Sasnauskas, K. and Buzaite, O. and Vogel, F. and Jandrig, B. and Razanskas, R. and Staniulis, J. and Scherneck, S. and Kruger, D.H. and Ulrich, R.
Biological Chemistry 380 : 381-386. 1 March 1999

Estradiol receptor and prognostic parameters of human breast cancer.
Goerlich, M. and Jandrig, B.
Neoplasma 46 : 112-116. 1 January 1999

Capsid protein-encoding genes of hamster polyomavirus and properties of the viral capsid.
Siray, H. and Ozel, M. and Jandrig, B. and Voronkova, T. and Jia, W. and Zocher, R. and Arnold, W. and Scherneck, S. and Krueger, D.H. and Ulrich, R.
Virus Genes 18 (1): 39-47. January 1999

1998

Deletions in the long arm of chromosome 10 in lymphomas with t(14;18): A pathogenetic role of the tumor suppressor genes PTEN/MMAC1 and MXI1?
Siebert, R. and Gesk, S. and Harder, S. and Ploetz, S. and Matthiesen, P. and Grote, W. and Schlegelberger, B. and Jandrig, B. and Grasmo-Wendler, U.H. and Scherneck, S. and Rosenwald, A. and Ott, G.
Blood 92 (11): 4487-4489. 1 December 1998

Detection of 6q deletions in breast carcinoma cell lines by fluorescence in situ hybridization.
Zhang, Y.M. and Matthiesen, P. and Siebert, R. and Harder, S. and Theile, M. and Scherneck, S. and Schlegelberger, B.
Human Genetics 103 : 727-729. 1 December 1998

The linked human elongation initiation factor 4A1 (EIF4A1) and CD68 genes map to chromosome 17p13.
Jones, E. and Quinn, C.M. and See, C.G. and Montgomery, D.S. and Ford, M.J. and Koelble, K. and Gordon, S. and Greaves, D.R.
Genomics 53 : 248-250. 15 October 1998

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations.
Lakhani, S.R. and Jacquemier, J. and Sloane, J.P. and Gusterson, B.A. and Anderson, T.J. and Vandevijver, M.J. and Farid, L.M. and Venter, D. and Antoniou, A. and Storferisser, A. and Smyth, E. and Steel, C.M. and Haites, N. and Scott, R.J. and Goldgar, D. and Neuhausen, S. and Daly, P.A. and Ormiston, W. and Mcmanus, R. and Scherneck, S. and Ponder, B.A.J. and Ford, D. and Peto, J. and Stoppa-Lyonnet, D. and Bignon, Y.J. and Struewing, J.P. and Spurr, N.K. and Bishop, D.T. and Klijn, J.G.M. and Devilee, P. and Cornelisse, C.J. and Lasset, C. and Lenoir, G. and Barkardottir, R.B. and Egilsson, V. and Hamann, U. and Changclaude, J. and Sobol, H. and Weber, B. and Stratton, M.R. and Easton, D.F.
Journal of the National Cancer Institute 90 (15): 1138-1145. 5 August 1998

Consortium study on 1280 breast carcinomas: Allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters.
Phelan, C.M. and Borg, A. and Cuny, M. and Crichton, D.N. and Baldersson, T. and Andersen, T.I. and Caligo, M.A. and Lidereau, R. and Lindblom, A. and Seitz, S. and Kelsell, D. and Hamann, K. and Rio, P. and Thorlacius, S. and Papp, J. and Olah, E. and Ponder, B. and Bignon, Y.J. and Scherneck, S. and Barkardottir, R. and Borresen-Dale, A.L. and Eyfjoerd, J. and Theillet, C. and Thompson, A.M. and Devilee, P. and Larsson, C.
Cancer Research 58 (5): 1004-1012. 1 March 1998

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families.
Ford, D. and Easton, D.F. and Stratton, M. and Narod, S. and Goldgar, D. and Devilee, P. and Bishop, D.T. and Weber, B. and Lenoir, G. and Chang-Claude, J. and Sobol, H. and Teare, M.D. and Struewing, J. and Arason, A. and Scherneck, S. and Peto, J. and Rebbeck, T.R. and Tonin, P. and Neuhausen, S. and Barkardottir, R. and Eyfjord, J. and Lynch, H. and Ponder, B.A.J. and Gayther, S.A. and Birch, J.M. and Lindblom, A. and Stoppa-Lyonnet, D. and Bignon, Y. and Borg, A. and Hamann, U. and Haites, N. and Scott, R.J. and Maugard, C.M. and Vasen, H. and Seitz, S. and Cannon-Albright, L.A. and Schofield, A. and Zelada-Hedman, M.
American Journal of Human Genetics 62 (3): 676-689. March 1998

Genetische Praedisposition beim Mammakarzinom.
Hofmann, W. and Schlag, P.M. and Scherneck, S.
Onkologe 4 : 868-877. 1 January 1998

Mammalian protein homologous to VAT-1 of torpedo californica: isolation from Ehrlich Ascites Tumor cells, biochemical characterization and organization of its gene.
Hayess, K. and Kraft, R. and Sachsinger, J. and Janke, J. and Jandrig, B. and Beckmann, G. and Rohde, K. and Benndorf, R.
Journal of Cellular Biochemistry 69 : 304-315. 1 January 1998

Mechanismen der Entstehung genetisch bedingter Krebsformen.
Scherneck, S. and Koelble, K.
In: Tumorerkrankungen. Handbuch der Molekularen Medizin ; 2 . Springer, Berlin [u.a.], 3-26. 1 January 1998

1997

Bedeutung molekulargenetischer Veränderungen für eine verbesserte Risikoabschätzung beim Brustkrebs.
Scherneck, S. and Jandrig, B.
In: Handbuch Onkologie : Grundlagen, Diagnostik, Therapie, Entwicklungen. ecomed, Landsberg/Lech, 1-21. ISBN 3-609-76300-0 December 1997

Microsatellite instability analysis: a multicenter study for reliability and quality control.
Bocker, T. and Diermann, J. and Friedl, W. and Gebert, J. and Holinski-Feder, E. and Karner-Hanusch, J. and von Knebel-Doeberitz, M. and Koelble, K. and Moeslein, G. and Schackert, H.K. and Witz, H.C. and Fishel, R. and Rueschoff, J.
Cancer Research 57 (21): 4739-4743. 1 November 1997

Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22: linkage analysis in german breast cancer families.
Seitz, S. and Rohde, K. and Bender, E. and Nothnagel, A. and Koelble, K. and Schlag, P.M. and Scherneck, S.
Oncogene 14 (6): 741-743. 13 February 1997

BRCA1 mutations and phenotype.
Grade, K. and Hoeffken, K. and Kath, R. and Nothnagel, A. and Bender, E. and Scherneck, S.
Journal of Cancer Research and Clinical Oncology 123 : 69-70. 1 January 1997

Deletion mapping and linkage analysis provide strong indication for the involvement of the human chromosome region 8p12-p22 in breast carcinogenesis.
Seitz, S. and Rohde, K. and Bender, E. and Nothnagel, A. and Pidde, H. and Ullrich, O.M. and El-Zehairy, A. and Haensch, W. and Jandrig, B. and Koelble, K. and Schlag, P.M. and Scherneck, S.
British Journal of Cancer 76 : 983-991. 1 January 1997

Generation of lymphoma-type variant hamster polyomavirus genomes in hamsters susceptible to lymphoma induction.
Prokoph, H. and Jandrig, B. and Arnold, W. and Scherneck, S.
Archives of Virology 142 : 53-63. 1 January 1997

Loss of heterozygosity at 7q31 in breast cancer: results from an international collaborative study group.
Devilee, P. and Hermans, J. and Eyfjoerd, J. and Borresen, A.L. and Liderau, R. and Sobol, H. and Borg, A. and Cleton-Jansen, A.M. and Olah, E. and Cohen, B. and Scherneck, S. and Hamann, U. and Peterlin, B. and Caligo, M. and Bignon, Y.L. and Maugard, C. and Andersen, T.I. and Odegand, A.E.M. and Bieche, I. and Birnbaum, D. and Cornelisse, C.J. and Sztan, M. and Steel, M.R. and Seitz, S. and Logar, N. and Golouh, R. and Ghimenti, C. and Bruelle, S. and Joalland, M.P.
Genes Chromosomes & Cancer 18 : 193-199. 1 January 1997

Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases.
Lakhani, S.R. and Easton, D.F. and Stratton, M.R. and Storferisser, A. and Anderson, T.J. and Farid, L.M. and Gusterson, B.A. and Jaquemier, J. and Sloane, J.P. and Venter, D. and Vandevijver, M.J. and Bishop, D.T. and Barkardottir, R.B. and Bignon, Y.J. and Cornelisse, C. and Changclaude, J. and Daly, P.A. and Devilee, P. and Egilsson, V. and Ford, D. and Goldgar, D. and Haites, N. and Hamann, U. and Klijn, J.G.M. and Lasset, C. and Lenoir, G. and Mcmanus, R. and Neuhausen, S. and Ormiston, W. and Ponder, B.A.J. and Peto, J. and Steel, C.M. and Stoppa-Lyonnet, D. and Smyth, E. and Sobol, H. and Spurr, N. and Scott, R.J. and Scherneck, S. and Streuwing, J.P. and Vasen, H. and Weber, B.
Lancet 349 : 1505-1510. 1 January 1997

Steroid hormone receptors and antineoplastic chemotherapy in human breast cancer.
Goerlich, M. and Jandrig, B.
Journal of Experimental & Clinical Cancer Research 16 : 95-103. 1 January 1997

1996

A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer.
Theile, M. and Seitz, S. and Arnold, W. and Jandrig, B. and Frege, R. and Schlag, P.M. and Haensch, W. and Guski, H. and Winzer, K.J. and Barrett, J.C. and Scherneck, S.
Oncogene 13 (4): 677-685. 15 August 1996

A novel mutation in the BRCA1 gene in a German early-onset breast cancer family.
Waindzoch, B. and Grade, K. and Jandrig, B. and Mueller, M. and Schlag, P.M. and Scherneck, S.
Human Mutation 8 : 393. 1 January 1996

BRCA1 mutation update and analysis.
Grade, K. and Jandrig, B. and Scherneck, S.
Journal of Cancer Research and Clinical Oncology 122 : 702-706. 1 January 1996

BRCA1 mutations in German breast-cancer families.
Jandrig, B. and Grade, K. and Seitz, S. and Waindzoch, B. and Mueller, M. and Bender, E. and Nothnagel, A. and Rohde, K. and Schlag, P.M. and Kath, R. and Hoeffken, K. and Scherneck, S.
International Journal of Cancer 68 : 188-192. 1 January 1996

Estradiol receptors and metastasis in human breast cancer.
Goerlich, M. and Jandrig, B.
Folia Biologica Prague 42 : 3-10. 1 January 1996

Genomic structure and chromosomal localization of the human interleukin 15 gene (IL 15).
Krause, H. and Jandrig, B. and Wernicke, C. and Bulfone-Paus, S. and Pohl, T. and Diamantstein, T.
Cytokine 8 : 667-674. 1 January 1996

Hamster polyomavirus encoded proteins: gene cloning, heterologous expression and immunoreactivity.
Ulrich, R. and Sommerfeld, K. and Schroeder, A. and Prokoph, H. and Arnold, W. and Krueger, D.H. and Scherneck, S.
Virus Genes 12 : 265-274. 1 January 1996

In vivo replication of hamster polyomavirus DNA displays lymphotropism in hamsters susceptible to lymphoma induction.
Prokoph, H. and Arnold, W. and Schwartz, A. and Scherneck, S.
Journal of General Virology 77 Part 9 : 2165-2172. 1 January 1996

Steroid hormone receptors and hormonal therapies in human breast cancer.
Goerlich, M. and Jandrig, B.
Journal of Experimental & Clinical Cancer Research 15 (1): 23-32. 1 January 1996

1995

TP53 mutations and breast cancer prognosis - particularly poor survival rates for cases with mutations in the zinc-binding domains.
Borresen, A.L. and Andersen, T.I. and Eyfjord, J.E. and Cornelis, R.S. and Thorlacius, S. and Borg, A. and Johansson, U. and Theillet, C. and Scherneck, S. and Hartman, S. and Cornelisse, C.J. and Hovig, E. and Devilee, P.
Genes Chromosomes & Cancer 14 (1): 71-75. September 1995

High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCA1-linked families.
Cornelis, R.S. and Neuhausen, S.L. and Johansson, O. and Arason, A. and Kelsell, D. and Ponder, B.A.J. and Tonin, P. and Hamann, U. and Lindblom, A. and Lalle, P. and Longy, M. and Olah, E. and Scherneck, S. and Bignon, Y.J. and Sobol, H. and Chang-Claude, J. and Larsson, C. and Spurr, N. and Borg, A. and Barkardottir, R.B. and Narod, S. and Devilee, P.
Genes Chromosomes & Cancer 13 (3): 203-210. 1 July 1995

Suppression of tumorigenicity of breast cancer cells by transfer of human chromosome 17 does not require transferred BRCA1 and p53 genes.
Theile, M. and Hartmann, S. and Scherthan, H. and Arnold, W. and Deppert, W. and Frege, R. and Glaab, F. and Haensch, W. and Scherneck, S.
Oncogene 10 (3): 439-447. 2 February 1995

A program using loss-of-constitutional- heterozygosity data to ascertain the location of predisposing genes in cancer families.
Rohde, K. and Teare, M.D. and Scherneck, S. and Santibanez-Koref, M.F.
Human Heredity 45 : 337-345. 1 January 1995

Contribution of molecular genetic changes for improved management of breast cancer.
Scherneck, S.
Onkologie 18 : 189-201. 1 January 1995

Klonierung des Brustkrebsgens BRCA1. Konsequenzen fuer Diagnostik und Klinik.
Chang-Claude, J. and Scherneck, S.
Deutsches Aerzteblatt 92 (37): A-2414-A-2418. 1 January 1995

No evidence for segregation distortion of cystic fibrosis alleles among sibs of cystic fibrosis patients.
Devoto, M. and Romeo, G. and Tankate, L.P. and Chevalier, F. and Bozon, D. and Estivill, X. and Casals, T. and Abeliovich, D. and Lerer, I. and Padoan, R. and Seia, M. and Hill, A. and Liechtigallati, S. and Kramer, R. and Beards, F. and Dear, S. and Dallapiccola, B. and Sangiuolo, F. and Macek, M. and McMahon, R. and Connarty, M. and Harvey, J.F. and Claustres, M. and Desgeorges, M. and Devries, R. and Scheffer, H. and Cankiklain, N. and Audrezet, M.P. and Bienvenu, T. and Chomel, J.C. and Dziadek, V. and Tummler, B. and Schwarz, M. and Haworth, A. and Benitez, J. and Fernandez, E. and Mazurczak, T. and Bal, J. and Cremonesi, L. and Ronchetto, P. and Cashman, S.M. and Ferec, C. and Cuppens, H. and Bauer, I. and Angelicheva, D. and Wagner, K. and Pacheco, P. and Bonizzato, A. and Witt, M. and McMahon, C.J. and Ravnikglavac, M. and Reis, A. and Stuhrmann, M. and Garnerone, S. and Curtis, A. and Gruning, G. and Kanavakis, E. and Klaassen, T. and Grade, K.
European Journal of Human Genetics 3 (5): 324-325. 1 January 1995

1994

Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
Futreal, P.A. and Cochran, C. and Marks, J.R. and Iglehart, J.D. and Zimmerman, W. and Barrett, J.C. and Wiseman, R.W.
Cancer Research 54 (7): 1791-1794. 1 April 1994

A 32-bp deletion (2991DEL32) in the cystic-fibrosis gene associated with CFTR messenger-RNA reduction.
Dork, T. and Will, K. and Grade, K. and Krawczak, M. and Tummler, B.
Human Mutation 4 : 65-70. 1 January 1994

Acceptability of carrier screening for cystic fibrosis during pregnancy in a German population.
Jung, U. and Urner, U. and Grade, K. and Coutelle, C.
Human Genetics 94 : 19-24. 1 January 1994

Diagnostics and screening of cystic fibrosis.
Grade, K. and Grunewald, I. and Urner, U. and Coutelle, C. and Graupner, I. and Jung, U. and Bittner, P. and Nebelung, W. and Leucht, B.
Bulletin of the Polish Acadmy of Sciences Biological Sciences 41 : 363-365. 1 January 1994

Identification of three novel mutations in the CFTR gene using temperature-optimized non-radioactive conditions for SSCP analysis.
Grade, K. and Grunewald, I. and Graupner, I. and Behrens, F. and Coutelle, C.
Human Genetics 94 : 154-158. 1 January 1994

Wild-Type p53 is not involved in reversion of the tumorigenic phenotype of breast cancer cells after transfer of normal chromosome 17.
Theile, M. and Hartmann, S. and Naundorf, H. and Ruebeta, D. and Elbe, B. and Krause, H. and Deppert, W. and Barrett, J.C. and Scherneck, S.
International Journal of Oncology 4 : 1067-1075. 1 January 1994

1993

Correlation between genotype and phenotype in patients with cystic fibrosis.
Hamosh, A. and Grade, K. and Coutelle, C. and Reis, A.
New England Journal of Medicine 329 (18): 1308-1313. 28 October 1993

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families.
Easton, D. and Bishop, D.T. and Ford, D. and Crockford, G.P. and Scherneck, S. and Zimmerman, W.
American Journal of Human Genetics 52 (4): 678-701. April 1993

Linkage analysis in German breast cancer families with early onset of the disease, using highly polymorphic markers from the chromosome 17q11-q24 region.
Zimmermann, W. and Bender, E. and Rohde, K. and Reis, A. and Wiseman, R. and Futreal, A. and Krause, H. and Prokoph, H. and Werner, S. and Scherneck, S.
American Journal of Human Genetics 52 (4): 789-791. April 1993

Spontane Wachstumshemmung beim Retinoblastom.
Lommatzsch, P.K. and Zimmermann, W. and Lommatzsch, R.
Klinische Monatsblaetter fuer Augenheilkunde 202 : 218-223. 1 March 1993

Mutations within the hamster polyomavirus large T antigen domain involved in pRb binding impair virus productive cycle and immortalization capacity.
Goutebroze, L. and De La Roche Saint Andre, C. and Scherneck, S. and Feunteun, J.
Oncogene 8 : 685-693. 1 January 1993

Non-isotopic analysis of single strand conformation polymorphism (SSCP) in the exon 13 region of the human dystrophin gene.
Lenk, U. and Hanke, R. and Kraeft, U. and Grade, K. and Grunewald, I. and Speer, A.
Journal of Medical Genetics 30 : 951-954. 1 January 1993

Virus-induced mesotheliomas in Syrian hamsters.
Arnold, W. and Scherneck, S.
European Respiratory Review 3 : 132-133. 1 January 1993

1992

Membrane transport in multidrug resistance, development, and disease. AACR Special Conference in Cancer Research.
Jandrig, B. and Wunderlich, V.
Journal of Cancer Research and Clinical Oncology 118 (3): 238-239. March 1992

Aspects moleculaires de la pathogenecite du polyomavirus de hamster.
De La Roche Saint Andre, C. and Goutebroze, L. and Scherneck, S. and Mazur, S. and Michiels, F. and Feunteun, J.
In: Colloque / Societe Francaise de Microbiologie, Section de Microbiologie Alimentaire ; 11. UNSPECIFIED, Paris, 151-155. 1 January 1992

1991

Identification and characterization of the hamster polyomavirus middle T antigen.
Courdneidge, S.A. and Goutebroze, L. and Cartwright, A. and Heber, A. and Scherneck, S. and Feunteun, J.
Journal of Virology 65 : 3301-3308. 1 January 1991

Tumorgene im Blick.
Scherneck, S. and Zimmermann, W.
Spectrum 22 : 20-23. 1 January 1991