Browse by Research Team

2024

Extraembryonic gut endoderm cells undergo programmed cell death during development.
Batki, J., Hetzel, S., Schifferl, D., Bolondi, A., Walther, M., Wittler, L., Grosswendt, S., Herrmann, B.G. and Meissner, A.
Nature Cell Biology 26 (6): 868-877. June 2024

Basal delamination during mouse gastrulation primes pluripotent cells for differentiation.
Sato, N., Rosa, V.S., Makhlouf, A., Kretzmer, H., Sampath Kumar, A., Grosswendt, S., Mattei, A.L., Courbot, O., Wolf, S., Boulanger, J., Langevin, F., Wiacek, M., Karpinski, D., Elosegui-Artola, A., Meissner, A., Zernicka-Goetz, M. and Shahbazi, M.N.
Developmental Cell 59 (10): 1252-1268.e13. 20 May 2024

SRRM2 splicing factor modulates cell fate in early development.
Carvalho, S., Zea-Redondo, L., Tang, T.C.C., Stachel-Braum, P., Miller, D., Caldas, P., Kukalev, A., Diecke, S., Grosswendt, S., Grosso, A.R. and Pombo, A.
Biology Open 13 (4): bio060415. April 2024

2020

Epigenetic regulator function through mouse gastrulation.
Grosswendt, S., Kretzmer, H., Smith, Z.D., Kumar, A.S., Hetzel, S., Wittler, L., Klages, S., Timmermann, B., Mukherji, S. and Meissner, A.
Nature 584 (7819): 102-108. 6 August 2020

Unblending of transcriptional condensates in human repeat expansion disease.
Basu, S., Mackowiak, S.D., Niskanen, H., Knezevic, D., Asimi, V., Grosswendt, S., Geertsema, H., Ali, S., Jerković, I., Ewers, H., Mundlos, S., Meissner, A., Ibrahim, D.M. and Hnisz, D.
Cell 181 (5): 1062-1079. 28 May 2020

2019

Molecular recording of mammalian embryogenesis.
Chan, M.M., Smith, Z.D., Grosswendt, S., Kretzmer, H., Norman, T.M., Adamson, B., Jost, M., Quinn, J.J., Yang, D., Jones, M.G., Khodaverdian, A., Yosef, N., Meissner, A. and Weissman, J.S.
Nature 570 (7759): 77-82. 6 June 2019

2017

Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles, J., Karaiskos, N., Praktiknjo, S.D., Grosswendt, S., Wahle, P., Ruffault, P.L., Ayoub, S., Schreyer, L., Boltengagen, A., Birchmeier, C., Zinzen, R., Kocks, C. and Rajewsky, N.
BMC Biology 15 (1): 44. 19 May 2017

Essentials of miRNA-dependent control of mRNA translation and decay, miRNA targeting principles, and methods for target identification.
Grosswendt, S. and Rajewsky, N.
In: Essentials of noncoding RNA in neuroscience: ontogenetics, plasticity of the vertebrate brain. Academic Press, London, 19-38. ISBN 978-012804402-5 2017

2014

Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.
Grosswendt, S., Filipchyk, A., Manzano, M., Klironomos, F., Schilling, M., Herzog, M., Gottwein, E. and Rajewsky, N.
Molecular Cell 54 (6): 1042-1054. 19 June 2014

2013

The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiation.
Solana, J., Gamberi, C., Mihaylova, Y., Grosswendt, S., Chen, C., Lasko, P., Rajewsky, N. and Aboobaker, A.A.
PLoS Genetics 9 (12): e1004003. December 2013