| Item Type: | Article | 
|---|---|
| Title: | Millimeter-scale genetic gradients and community-level molecular convergence in a hypersaline microbial mat | 
| Creators Name: | Kunin, V., Raes, J., Harris, J.K., Spear, J.R., Walker, J.J., Ivanova, N., von Mering, C., Bebout, B.M., Pace, N.R., Bork, P. and Hugenholtz, P. | 
| Abstract: | To investigate the extent of genetic stratification in structured microbial communities, we compared the metagenomes of 10 successive layers of a phylogenetically complex hypersaline mat from Guerrero Negro, Mexico. We found pronounced millimeter-scale genetic gradients that were consistent with the physicochemical profile of the mat. Despite these gradients, all layers displayed near-identical and acid-shifted isoelectric point profiles due to a molecular convergence of amino-acid usage, indicating that hypersalinity enforces an overriding selective pressure on the mat community. | 
| Keywords: | Amino Acids, Microbial Genetics, Mexico, Salinity, Selection (Genetics) | 
| Source: | Molecular Systems Biology | 
| ISSN: | 1744-4292 | 
| Publisher: | Nature Publishing Group | 
| Volume: | 4 | 
| Page Range: | 198 | 
| Date: | 2008 | 
| Official Publication: | https://doi.org/10.1038/msb.2008.35 | 
| PubMed: | View item in PubMed | 
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