Plasmodium motility: actin not actin' like actin

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Item Type:	Article
Title:	Plasmodium motility: actin not actin' like actin
Creators Name:	Schueler, H. and Matuschewski, K.
Abstract:	Apicomplexan parasites such as Plasmodium and Toxoplasma display actomyosin-dependent motility in the absence of readily detectable actin polymers. Three recent studies indicate that parasite actin polymers, either harvested from parasites or formed from purified recombinant proteins, are exceptionally short ( approximately 100 nm). We propose that parasite motility could be directed by the transient formation of short actin filament scaffolds. Parasite actin polymers that support transmembrane receptors are pulled, by myosin interaction, backwards along the parasite periphery, resulting in forward movement.
Keywords:	Actins, Actomyosin, Microfilaments, Movement, Plasmodium, Animals
Source:	Trends in Parasitology
ISSN:	1471-4922
Publisher:	Elsevier
Volume:	22
Number:	4
Page Range:	146-147
Date:	April 2006
Official Publication:	https://doi.org/10.1016/j.pt.2006.02.005
PubMed:	View item in PubMed

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