Item Type: | Editorial |
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Title: | Pardon me - No access without ubiquitin |
Creators Name: | Sommer, T. and Jarosch, E. |
Abstract: | Spatial separation of ubiquitin conjugation pathways contributes to target-specific ubiquitination. Recently, Plafker et al. reported that importin 11-dependent nuclear import of the ubiquitin-conjugating enzyme UbcM2 occurs only if the latter is charged with ubiquitin. This interesting finding describes a link between nuclear transport pathways and ubiquitin and reveals a novel mechanism for localizing components of the ubiquitin system within the cell. |
Keywords: | Cell Nucleus Active Transport, Karyopherins, Signal Transduction, Ubiquitin, Ubiquitin-Conjugating Enzymes, Animals |
Source: | Developmental Cell |
ISSN: | 1534-5807 |
Publisher: | Cell Press |
Volume: | 8 |
Number: | 1 |
Page Range: | 4-5 |
Date: | 1 January 2005 |
PubMed: | View item in PubMed |
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