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Teilkoerperhyperthermie mit einem Radiofrequenz-Multiantennen-Applikator unter online Kontrolle in einem 1,5 T MR-Tomographen [Part-body hyperthermia with a radiofrequency multiantenna applicator under online control in a 1.5 T MR-tomograph]

Item Type:Article
Title:Teilkoerperhyperthermie mit einem Radiofrequenz-Multiantennen-Applikator unter online Kontrolle in einem 1,5 T MR-Tomographen [Part-body hyperthermia with a radiofrequency multiantenna applicator under online control in a 1.5 T MR-tomograph]
Creators Name:Wust, P., Gellermann, J., Seebass, M., Faehling, H., Turner, P., Wlodarczyk, W., Nadobny, J., Rau, B., Hildebrandt, B., Oppelt, A., Schlag, P.M. and Felix, R.
Abstract:Objective of this study is the integration of a multiantenna applicator for part-body hyperthermia (BSD 2000/3D) in a 1.5 T MR-­tomograph (Siemens Magnetom Symphony) in order to perform noninvasive MR monitoring in real time to increase safety and effectiveness of heat treatments. The positioning unit is mechan­ically coupled to the MR gantry from the back side and the body coil is utilised for imaging. For that purpose, the hyperthermia antenna system (100 MHz, 1.500 W) and the MR receiver (63.9 MHs) have to be decoupled in terms of high frequency (filter) and electromagnetically (emc). The processing of MR data sets is performed in a hyperthermia planning system. A simultaneous operation of radiofrequency hyperthermia and MR system is possible at cli­nically relevant power levels. MR imaging is used for tumor ­diagnostics (standard spin echo sequences), for hyperthermia planning (T1-weighted gradient echo sequences in equal- and opposed-phase techniques), and for temperature measurements according to the proton resonance frequency method (PRF method, phase evaluation registration using a gradient echo sequence with long echo time). In 33 patients with advanced pelvic and abdominal tumors we performed 150 heat sessions under MR monitoring. For 70 % of these patients a visualisation of temperature sensitive data during treatment was possible. The evaluated difference images represent a superposition of real temperature ­increase and a (temperature-induc­ed) perfusion elevation. The ­hyprid approach renders development of part body hyperthermia possible as an MR-controlled intervention in radiology.
Keywords:Noninvasive MR-Thermometry, Part Body Hyperthermia, Multi-Antenna Applicator, MR-Controlled Intervention
Source:RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren
ISSN:1438-9029
Volume:176
Number:3
Page Range:363-374
Date:1 March 2004
Official Publication:https://doi.org/10.1055/s-2004-812736
PubMed:View item in PubMed

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