Item Type: | Editorial |
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Title: | Hip1 and Hippi participate in a novel cell death-signaling pathway |
Creators Name: | Wanker, E.E. |
Abstract: | Neuronal apoptosis is a cardinal feature of late-onset neurodegenerative disorders such as Alzheimers and Huntington's disease. Biochemical and cell biological studies point to a role for Hip1 and Hippi in caspase-8 activation and the initiation of apoptosis during the pathogenesis of Huntington's disease. |
Keywords: | Apoptosis, Caspases, DNA-Binding Proteins, Huntington Disease, Signal Transduction |
Source: | Developmental Cell |
ISSN: | 1534-5807 |
Publisher: | Cell Press |
Volume: | 2 |
Number: | 2 |
Page Range: | 126-128 |
Date: | February 2002 |
Official Publication: | https://doi.org/10.1016/S1534-5807(02)00121-1 |
PubMed: | View item in PubMed |
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