SMART: a web-based tool for the study of genetically mobile domains

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Item Type:	Article
Title:	SMART: a web-based tool for the study of genetically mobile domains
Creators Name:	Schultz, J., Copley, R.R., Doerks, T., Ponting, C.P. and Bork, P.
Abstract:	SMART (a Simple Modular Architecture Research Tool) allows the identification and annotation of genetically mobile domains and the analysis of domain architectures (http://SMART.embl-heidelberg.de ). More than 400 domain families found in signalling, extra-cellular and chromatin-associated proteins are detectable. These domains are extensively annotated with respect to phyletic distributions, functional class, tertiary structures and functionally important residues. Each domain found in a non-redundant protein database as well as search parameters and taxonomic information are stored in a relational database system. User interfaces to this database allow searches for proteins containing specific combinations of domains in defined taxa.
Keywords:	Database Management Systems, Information Storage and Retrieval, Proteins, Chemistry, Sequence Alignment
Source:	Nucleic Acids Research
ISSN:	0305-1048
Publisher:	Oxford University Press
Volume:	28
Number:	1
Page Range:	231-234
Date:	1 January 2000
Official Publication:	http://nar.oxfordjournals.org/cgi/content/abstract/28/1/231
PubMed:	View item in PubMed

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