Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

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Item Type:	Article
Title:	Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
Creators Name:	Birchmeier, C. and Gherardi, E.
Abstract:	A number of developmental processes that involve cell migration, growth or morphogenesis depend on extracellular signals. A molecule that provides such signals, known as hepatocyte growth factor/scatter factor (HGF/SF), has attracted considerable interest in recent years because of its distinct structure, mechanism of activation and important roles throughout embryogenesis. This review discusses the main features of HGF/SF and its receptor, the product of the c-met protooncogene, and their role in embryogenesis.
Keywords:	Cell Behaviour, Cell Differentiation, Cell Motility, Scatter Factor, Hepatocyte Growth Factor (HGF), Met Receptor, Plasminogen-Related Growth Factors, Animals, Mice
Source:	Trends in Cell Biology
ISSN:	0962-8924
Publisher:	Elsevier
Volume:	8
Number:	10
Page Range:	404-410
Date:	1 October 1998
Official Publication:	https://doi.org/10.1016/S0962-8924(98)01359-2
PubMed:	View item in PubMed

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