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| Item Type: | Editorial |
|---|---|
| Title: | More than fuel: metabolic states shape cell fate in the human neocortex |
| Creators: |
Bicci, Iacopo  ORCID: https://orcid.org/0000-0001-6994-3857 and Gouti, Mina ORCID: https://orcid.org/0000-0001-7422-1605
|
| Abstract: | Do metabolic changes follow cell fate decisions during human corticogenesis, or do they actively specify them? Publishing in Cell, Mil et al.1 combine primary human cortical tissue and cortical organoids to reveal developmentally regulated metabolic states and show that glycolysis and pentose phosphate pathway activity shape radial glia fate decisions. |
| Keywords: | Cell Differentiation, Cell Lineage, Glycolysis, Neocortex, Pentose Phosphate Pathway |
| Source: | Developmental Cell |
| ISSN: | 1534-5807 |
| Publisher: | Cell Press / Elsevier |
| Volume: | 61 |
| Number: | 10 |
| Page Range: | 1943-1944 |
| Date: | 14 October 2026 |
| Official Publication: | https://doi.org/10.1016/j.devcel.2026.09.009 |
| PubMed: | View item in PubMed |
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