PXD074772: Myeloid cell recruitment propels right ventricular dysfunction in HFpEF via sterile inflammation

Tools

Item Type:	Dataset
Title:	PXD074772: Myeloid cell recruitment propels right ventricular dysfunction in HFpEF via sterile inflammation
Creators:	Fahjen, Pauline ORCID: https://orcid.org/0000-0002-5015-0643 and Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X
Abstract:	This project characterizes chamber-specific proteomic remodeling in a murine three-hit HFpEF model that develops right ventricular dysfunction, using chow, hypoxia alone, and HFD+L-NAME as control conditions. The three-hit model (hypoxia, high-fat diet, and L-NAME) recapitulates key features of human HFpEF, including left ventricular diastolic dysfunction and secondary right ventricular hypertrophy and dysfunction.
Keywords:	Heart, Mouse, Hfpef, Hypoxia
Source:	PRIDE
Publisher:	EMBL-EBI
Date:	7 September 2026
External Fulltext:	View full text on external repository or document server
Related to:	URL URL Type https://edoc.mdc-berlin.de/26829/ Publication

Repository Staff Only: item control page