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Actin rings of power

Item Type:Review
Title:Actin rings of power
Creators: Schwayer, Cornelia ORCID logoORCID: https://orcid.org/0000-0001-5130-2226, Sikora, Mateusz, Slováková, Jana, Kardos, Roland and Heisenberg, Carl-Philipp
Abstract:Circular or ring-like actin structures play important roles in various developmental and physiological processes. Commonly, these rings are composed of actin filaments and myosin motors (actomyosin) that, upon activation, trigger ring constriction. Actomyosin ring constriction, in turn, has been implicated in key cellular processes ranging from cytokinesis to wound closure. Non-constricting actin ring-like structures also form at cell-cell contacts, where they exert a stabilizing function. Here, we review recent studies on the formation and function of actin ring-like structures in various morphogenetic processes, shedding light on how those different rings have been adapted to fulfill their specific roles.
Keywords:Actin Cytoskeleton, Actins, Cell Adhesion, Cytokinesis, Wound Healing, Animals
Source:Developmental Cell
ISSN:1534-5807
Publisher:Cell Press
Volume:37
Number:6
Page Range:493-506
Date:20 June 2016
Official Publication:https://doi.org/10.1016/j.devcel.2016.05.024
PubMed:View item in PubMed

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