Copyright (c) 2026 Daniel León-Periñán, Nikolaos  Karaiskos  and
Nikolaus  Rajewsky  Max  Delbrück Center for Molecular  Medicine
(MDC), Berlin, Germany

MDC (Licensor) grants to Licensee free of charge a non‐exclusive,
non‐transferable, non‐sublicensable right and license to use com‐
puter software called MALVA (the "Software") solely for  internal
academic  purposes (the "Licensed Use") under the following terms
and conditions.

For the purposes of this Agreement, Licensed Use  means  non‐com‐
mercial  research, teaching, scientific evaluation and validation
conducted within a university or other non‐profit research insti‐
tution. Licensed Use exclude, without limitation, commercial  re‐
search,  clinical  use,  diagnostics  use,  contract research for
third parties, provision of services to third parties, use  in  a
commercial product or service, or any use intended to obtain com‐
mercial advantage or monetary compensation.

1. Grant of license:
   Licensee may
   a.   install,  copy,  modify, and/or create derivatives of the
Software, in source code and/or object code form, solely for  the
Licensed  Use  on computers or systems owned, leased or otherwise
controlled by Licensee. Any modifications  or  derivatives  shall
remain subject to the terms of this Agreement;
   b.   make such copies of the Software as are reasonably neces‐
sary for backup, archival and internal research purposes;
   c.   publish  scientific  results  obtained through use of the
Software, provided that no confidential information  or  substan‐
tial portions of the Software source code are disclosed. Publica‐
tions  resulting from the use of the Software shall appropriately
cite the  corresponding  scientific  publication  describing  the
Software in accordance to good scientific practice;
   d.   include  the  above  copyright notice and this permission
notice in all copies or substantial portions of the Software.

2. Restrictions: 
   Licensee shall not
   a.   Use, reproduce, distribute, modify or exploit  the  Soft‐
ware or any derivatives thereof except as expressly permitted un‐
der  this  Agreement. commercial use including but not limited to
use in a commercial product or service, use by a  for‐profit  en‐
tity or use to generate revenue is expressly prohibited without a
separate  written  license  (for  commercial licensing inquiries,
contact:    Daniel    LeÃ³n‐PeriÃ±Ã¡n     daniel.leonperinan@mdc‐
berlin.de).
   b.   reverse  engineer,  decompile or disassemble the Software
in object code format, source code format or merge  any  part  of
the Software except to the extent expressly permitted by applica‐
ble mandatory law;
   c.   rent,  lease, sell, sub‐license, assign, transfer or oth‐
erwise grant any rights in the Software to any third party;
   d.   remove, alter obscure any copyright  notices,  labels  or
other  trademarks  from  the Software or other materials received
from MDC; or
   e.   make the Software, in whole or in part, available to  any
third party without MDC’s prior written consent.
   Any breach of this Agreement shall automatically terminate the
rights granted under this License.

3. Intellectual Property Rights
   a.   Title  to  and  ownership  to  the Software including all
copyrights, patent rights, trade  secrets  and  other  IP  rights
shall remain exclusively with MDC.
   b.   Except for the rights expressly granted under this Agree‐
ment,  no  rights or licenses are granted, whether express or im‐
plied.

4. Responsibility
   a.   Licensee shall be solely responsible for  the  management
and  control of its use of the Software including but not limited
to determining the suitability of the Software for  its  intended
research  purposes and ensuring that the Software is used only by
appropriately qualified personnel.
   b.   Licensee shall be solely responsible  for  the  accuracy,
completeness and compliance of all data processed using the Soft‐
ware,  the input of such data and the application of all informa‐
tion provided by the Software.

THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF  ANY  KIND,
EXPRESS  OR  IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES
OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE  AND  NONIN‐
FRINGEMENT.  IN  NO EVENT SHALL MDC BE LIABLE FOR ANY CLAIM, DAM‐
AGES ARISING FROM, OUT OF OR IN CONNECTION WITH THE  SOFTWARE  OR
ITS USE.